Evidence map›Paper›PMID 34690780›Full record

ArticleFrontiers in pharmacology2021

FDX1 can Impact the Prognosis and Mediate the Metabolism of Lung Adenocarcinoma.

Zeyu Zhang, Yarui Ma, Xiaolei Guo, Yingxi Du, Qing Zhu, Xiaobing Wang, Changzhu Duan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
114citing papers in PubMed, 1 pooled it
20.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

114 citing papers in PubMed, 1 synthesis or guideline pooled it, 209 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Copper dysregulation in cardiometabolic disease: copper deficiency versus cuproptosis.Apoptosis : an international journal on programmed cell death · 2026
    Review
  5. Role of Ferredoxin 1Cancer pathogenesis and therapy · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Review
  15. Involvement of copper in cell death and cancer.Apoptosis : an international journal on programmed cell death · 2025
    Review
  16. Article
  17. Oncology research · 2025
    Article
  18. Cuproptosis: Mechanism and Application in Lymphoma.Current cancer drug targets · 2025
    Review
  19. Review
  20. Article

54 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Zeyu ZhangDepartment of the First Clinical Medicine, Chongqing Medical University, Chongqing, China.
Yarui MaDepartment of Medical Oncology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, China.
Xiaolei GuoBinzhou Polytechnic, Binzhou, China.
Yingxi DuState Key Lab of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Qing ZhuDepartment of Clinical Laboratory, Beijing Friendship Hospital, Capital Medical University, Beijing, China.
Xiaobing WangState Key Lab of Molecular Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Changzhu DuanDepartment of Cell Biology and Genetics, Medicine and Cancer Research Center, Chongqing Medical University, Chongqing, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNChongqing Medical University · CNBeijing Friendship Hospital · CNYangzhou Polytechnic Institute · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

inflammatory responselung cancermetabolismmitochondria electron transport chainrisk signature

Identifiers

PMID34690780
PMCPMC8531531
OpenAlexW3206018533

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.