Evidence mapPaperPMID 34693236Full record

ArticleJHEP reports : innovation in hepatology2021

Non-alcoholic fatty liver disease: A patient guideline.

Sven M Francque, Giulio Marchesini, Achim Kautz, Martine Walmsley, Rebecca Dorner, Jeffrey V Lazarus, Shira Zelber-Sagi, Kate Hallsworth, Luca Busetto, Gema Frühbeck and 9 more

Erratum issuedAbstract read
In one paragraph

Article in JHEP reports : innovation in hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 129 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
129citing papers in PubMed, 3 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

129 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Guideline
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  20. Name MASLD/MASH - and act on it.Hepatology communications · 2026
    Article

69 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Sven M FrancqueDepartment of Gastroenterology and Hepatology, Antwerp University Hospital, Antwerp, Belgium.
Giulio MarchesiniIRCCS Azienda Ospedaliero-Universitaria di Bologna, Italy.
Achim KautzKautz gUG, Cologne, Germany.
Martine WalmsleyPSC Support, Oxford, United Kingdom.
Rebecca DornerKautz gUG, Cologne, Germany.
Jeffrey V LazarusBarcelona Institute for Global Health (ISGlobal), Hospital Clínic, University of Barcelona, Spain.
Shira Zelber-SagiSchool of Public Health, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel.
Kate HallsworthNewcastle NIHR Biomedical Research Centre, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.
Luca BusettoDepartment of Medicine, University of Padova, Italy.
Gema FrühbeckDepartment of Endocrinology & Nutrition, University of Navarra Clinic, IdiSNA, CIBEROBN, Pamplona, Spain.
Dror DickerDepartment of Internal Medicine, Rabin Medical Center Hasharon Hospital, Tikva, Israel.
Euan WoodwardEuropean Association for the Study of Obesity.
Marko KorenjakEuropean Liver Patients' Association.
José WillemseLiver Patients International.
Gerardus H KoekDepartment of Internal Medicine, Division of Gastroenterology and Hepatology, Maastricht University Medical Centre, Maastricht, the Netherlands.
Shlomo VinkerDepartment of Family Medicine, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Mehmet UnganWorld Organization of Family Doctors (WONCA).
Juan M MendiveTraining Unit of Family Medicine, Catalan Institute of Health, Barcelona, Spain.
Christos LionisEuropean Society for Primary Care Gastroenterology.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This patient guideline is intended for all patients at risk of or living with non-alcoholic fatty liver disease (NAFLD). NAFLD is the most frequent chronic liver disease worldwide and comes with a high disease burden. Yet, there is a lot of unawareness. Furthermore, many aspects of the disease are still to be unravelled, which has an important impact on the information that is given (or not) to patients. Its management requires a close interaction between patients and their many healthcare providers. It is important for patients to develop a full understanding of NAFLD in order to enable them to take an active role in their disease management. This guide summarises the current knowledge relevant to NAFLD and its management. It has been developed by patients, patient representatives, clinicians and scientists and is based on current scientific recommendations, intended to support patients in making informed decisions.

Indexed as

ALD, alcohol-related or alcoholic liver diseaseASH, alcoholic steatohepatitisBMI, body mass indexCAP, controlled attenuation parameterCT, computed tomographyCVD, cardiovascular diseaseEASD, European Association for the Study of DiabetesEASL, European Association for the Study of the LiverEASO, European Association for the Study of ObesityFIB-4, fibrosis-4 indexFXR, farnesoid X receptorGLP-1 RAs, glucagon-like receptor 1 agonistsGP, general practitionerHCC, hepatocellular carcinomaHDL, high-density lipoproteinLDL, low-density lipoproteinsMRE, magnetic resonance elastographyMRI, magnetic resonance imagingNAFLD, non-alcoholic fatty liver diseaseNAFL, non-alcoholic fatty liverNASH CRN, NASH Clinical Research NetworkNASH, non-alcoholic steatohepatitisNIT, non-invasive testSMART, specific, measurable, achievable, relevant, timelyT1D, type 1 diabetesT2D, type 2 diabetes

Identifiers

PMID34693236
PMCPMC8514420

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.