ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021
Dynamic Rhythmogenic Network States Drive Differential Opioid Responses in the
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed.
- Partially countering the physiological effects of fentanyl with naloxone or d-cysteine ethyl ester in adult goats.Journal of applied physiology (Bethesda, Md. : 1985) · 2026Article
- Outcompeting opioid-induced respiratory depression.Journal of thoracic disease · 2026Article
- Nonclinical human neural new approach methodologies (NAMs): Electrophysiological assessment of opioid agonist and antagonist combination.NAM journal · 2025Article
- Functional modulation of retrotrapezoid neurons drives fentanyl-induced respiratory depression.American journal of physiology. Lung cellular and molecular physiology · 2025Article
- Neuroanatomical and neurochemical organization of brainstem and forebrain circuits involved in breathing regulation.Journal of neurophysiology · 2025Review
- Endomorphin-2 (Endo2) and substance P (SubP) co-application attenuates SubP-induced excitation and alters frequency plasticity in neonatal rat in vitro preparations.Respiratory physiology & neurobiology · 2025Article
- Article
- Disinhibition does not play a role in endomorphin-2-induced changes in inspiratory motoneuron output produced by in vitro neonatal rat preparations.Respiratory physiology & neurobiology · 2024Article
- A comparative examination of morphine and fentanyl: unravelling the differential impacts on breathing and airway stability.The Journal of physiology · 2023Article
- Purinergic signaling mediates neuroglial interactions to modulate sighs.Nature communications · 2023Article
- Breathing Rhythm and Pattern and Their Influence on Emotion.Annual review of neuroscience · 2022Review
- Inspiratory rhythm generation is stabilized byJournal of neurophysiology · 2022Article
- Mu-opioid receptor-dependent transformation of respiratory motor pattern in neonatesFrontiers in physiology · 2022Article
- Prostaglandin E2 Exerts Biphasic Dose Response on the PreBötzinger Complex Respiratory-Related Rhythm.Frontiers in neural circuits · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Death from opioid overdose is typically caused by opioid-induced respiratory depression (OIRD). A particularly dangerous characteristic of OIRD is its apparent unpredictability. The respiratory consequences of opioids can be surprisingly inconsistent, even within the same individual. Despite significant clinical implications, most studies have focused on average dose-r esponses rather than individual variation, and there remains little insight into the etiology of this apparent unpredictability. The preBötzinger complex (preBötC) in the ventral medulla is an important site for generating the respiratory rhythm and OIRD. Here, using male and female C57-Bl6 mice
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.