ArticleHandbook of experimental pharmacology2022
Obesity and Obstructive Sleep Apnea.
Article in Handbook of experimental pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
64 citing papers in PubMed, 4 syntheses or guidelines pooled it, 112 citations in OpenAlex.
- Sleep and the Mediterranean diet: A systematic review and meta-analysis.Sleep medicine reviews · 2025Pooled it
- Global prevalence of obesity and overweight among medical students: a systematic review and meta-analysis.BMC public health · 2024Pooled it
- Are Emotional Eating and Other Eating Behaviors the Missing Link in the Relationship between Inadequate Sleep and Obesity? A Systematic Review.Nutrients · 2023Pooled it
- Inspiratory muscle training in patients with obesity: a systematic review and meta-analysis.Frontiers in medicine · 2023Pooled it
- Nurse-managed telemonitoring in patients with sleep apnea syndrome treated with positive pressure ventilation.Sleep & breathing = Schlaf & Atmung · 2025Trial
- Association between insulin resistance and obstructive sleep apnea in non-diabetic children with obesity.European journal of pediatrics · 2026Article
- Sleep-Disordered Breathing and Decreased Bone Mineral Density: Masking Effects of Body Mass Index.Obesity facts · 2026Article
- Exploring the Linear and Non-linear Association Between BMI and Night-Time Blood Pressure Variability.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026Article
- Association Between Obstructive Sleep Apnea and Preoperative Cardiopulmonary Fitness in Patients Undergoing Sleeve Gastrectomy: A Real-World Study.Obesity surgery · 2026Article
- Relationship between body weight and daytime sleepiness in patients with untreated OSA: The role of hypoventilation due to obesity.Sleep & breathing = Schlaf & Atmung · 2026Article
- Disordered eating in office workers is correlated with trauma, stress, emotional regulation, and sleep quality: a cross-sectional screening.AIMS public health · 2026Article
- Clinical characteristics and pregnancy outcomes in polycystic ovary syndrome complicated by obstructive sleep apnea: a correlative study.Frontiers in medicine · 2026Article
- Obstructive Sleep Apnea and Subclinical Ischemic Heart Disease Risk in Obese Adults: Findings from an International Cross-Sectional Study.Juntendo medical journal · 2026Article
- Determination of the 95% Effective Dose of Remifentanil for Moderate Sedation During Gastroscopy in Obese Patients.Current medicinal chemistry · 2026Article
- Assessing the application potential of different species as obstructive sleep apnea models: a comparative analysis based on cranial CT anatomy.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025Article
- Research advances in the association between Irisin and obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2025Review
- Testosterone and Obesity in an Aging Society.Biomolecules · 2025Review
- Female predominance in nocturnal hypoxemia among elderly OSAS patients: hemoglobin mediates sex-specific hypoxic burden in Chinese cohorts.BMC geriatrics · 2025Article
- Abnormalities in the genioglossus muscle and its neuromuscular synapse in leptin-deficient male mice.Skeletal muscle · 2025Article
- Assessment of Tonsillar Hypertrophy, Tongue Position, Obesity, and Dentofacial Deformities among Children Aged 8-12 Years.International journal of clinical pediatric dentistry · 2025Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Obstructive sleep apnea (OSA) is characterized by upper airway collapse during sleep. Chronic intermittent hypoxia, sleep fragmentation, and inflammatory activation are the main pathophysiological mechanisms of OSA. OSA is highly prevalent in obese patients and may contribute to cardiometabolic risk by exerting detrimental effects on adipose tissue metabolism and potentiating the adipose tissue dysfunction typically found in obesity. This chapter will provide an update on: (a) the epidemiological studies linking obesity and OSA; (b) the studies exploring the effects of intermittent hypoxia and sleep fragmentation on the adipose tissue; (c) the effects of OSA treatment with continuous positive airway pressure (CPAP) on metabolic derangements; and (d) current research on new anti-diabetic drugs that could be useful in the treatment of obese OSA patients.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.