Observational studyThe Journal of clinical endocrinology and metabolism2022
Variations in Sleep Characteristics and Glucose Regulation in Young Adults With Type 1 Diabetes.
Observational study in The Journal of clinical endocrinology and metabolism, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The trial behind it
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Who cites it
19 citing papers in PubMed, 28 citations in OpenAlex.
- Psychosocial outcomes among adults with type 1 diabetes using a tubeless automated insulin delivery system compared with sensor augmented pump therapy: A randomised, parallel-group clinical trial sub-study.Diabetes, obesity & metabolism · 2026Trial
- Trial
- Sleep-AID: a cross-sectional analysis of subjective sleep quality, psychosocial measures and real-world glycemic outcomes in people with diabetes using automated insulin delivery systems.Sleep advances : a journal of the Sleep Research Society · 2026Article
- Sugar slay: a gamified decision support ecosystem for type 1 diabetes.Frontiers in digital health · 2026Article
- Multidimensional Sleep Health, Glycemic Control, and Self-reported Outcomes in Type 1 Diabetes: A Cross-sectional Study.The Journal of clinical endocrinology and metabolism · 2025Article
- Insulin Resistance in Type 1 Diabetes: Pathophysiological, Clinical, and Therapeutic Relevance.Endocrine reviews · 2025Review
- Sleep patterns in adults and children with less common forms of diabetes.Frontiers in endocrinology · 2025Review
- Sleep Disturbances in Type 1 Diabetes and Mitigating Cardiovascular Risk.The Journal of clinical endocrinology and metabolism · 2024Review
- Exploring Determinants of Health-Related Quality of Life in Emerging Adults with Type 1 Diabetes Mellitus: A Cross-Sectional Analysis.Nutrients · 2024Article
- Association between sleep variability and time in range of glucose levels in patients with type 1 diabetes: Cross-sectional study.Sleep health · 2023Article
- A composite measure of sleep health is associated with glycaemic target achievement in young adults with type 1 diabetes.Journal of sleep research · 2023Article
- Cognitive Behavioral Sleep Self-Management Intervention for Young Adults With Type 1 Diabetes (NCT04975230).Clinical nursing research · 2023Article
- Objective sleep characteristics and continuous glucose monitoring profiles of type 2 diabetes patients in real-life settings.Diabetes, obesity & metabolism · 2023Article
- Impact of Sleep and Activity on Glycemic Control and Quality of Life in Haitian Children and Youth with Type 1 Diabetes.Pediatric diabetes · 2023Article
- Evaluating the influence of sleep quality and quantity on glycemic control in adults with type 1 diabetes.Frontiers in endocrinology · 2023Observational
- Objective Sleep-Wake Characteristics Are Associated With Diabetes Symptoms in Young Adults With Type 1 Diabetes.The science of diabetes self-management and care · 2022Article
- Glucose and unstructured physical activity coupling during sleep and wake in young adults with type 1 diabetes.Scientific reports · 2022Article
- Review
- Sex Differences in Depression and Sleep Disturbance as Inter-Related Risk Factors of Diabetes.Frontiers in clinical diabetes and healthcare · 2022Article
Corrections and comments
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Authors and funding
9 authors at 6 institutions in 1 country.
Funding
Abstract
contextShort sleep duration and sleep disruptions are associated with impaired glucoregulation in type 1 diabetes (T1D). However, the mechanistic pathways between sleep and glucose variability remain unclear.
objectiveTo determine within- and between-person associations between objective sleep-wake characteristics and glucose variability indices.
methodsMultilevel models were used to analyze concurrent sleep and glucose patterns over 7 days in 42 young adults with T1D in their natural home environment. Young adults with T1D (mean age 22.2 ± 3.0 years, HbA1c 7.2%, 32.6% male) for at least 6 months with no other medical or major psychiatric comorbidity were included. Sleep-wake characteristics were measured via wrist actigraphy and glucose variability indices via a continuous glucose monitor (CGM).
resultsLower sleep efficiency predicted higher glucose variability (less time in range β = 0.011 and more time in hyperglycemia β = -0.011) within-person. A longer wake after sleep onset and more sleep disruptions were associated with higher glucose variability between persons (β = 0.28 and 0.31). Higher glucose variability predicted poorer sleep within-person (delayed bedtime, waketime, mid-sleep time, and lower sleep efficiency), while higher glucose variability was associated with poorer sleep and more sleep disruptions between persons (lower sleep efficiency, longer wake after sleep onset, and a higher sleep fragmentation index).
conclusionClinicians can address the reciprocal nature of the sleep-glucose relationship by optimizing sleep and targeting efforts toward a euglycemic range overnight. Sleep habits are a modifiable personal target in diabetes care.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.