Evidence mapPaperPMID 34700172Full record

SynthesisClinical imaging2022

Brain MRI findings in COVID-19 patients with PRES: A systematic review.

Rubaya Yeahia, Javin Schefflein, Patrick Chiarolanzio, Anna Rozenstein, William Gomes, Sana Ali, Hasit Mehta, Fawaz Al-Mufti, Andrew McClelland, Edwin Gulko

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in Clinical imaging, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Rubaya YeahiaNew York Medical College, Valhalla, New York, United States of America.
Javin ScheffleinDivision of Neuroradiology, Department of Radiology, Westchester Medical Center, Valhalla, New York, United States of America.
Patrick ChiarolanzioDepartment of Radiology, New York Medical College, Valhalla, New York, United States of America.
Anna RozensteinDivision of Cardiothoracic Radiology, Department of Radiology, Westchester Medical Center, Valhalla, New York, United States of America.
William GomesDivision of Neuroradiology, Department of Radiology, Westchester Medical Center, Valhalla, New York, United States of America.
Sana AliDivision of Neuroradiology, Department of Radiology, Westchester Medical Center, Valhalla, New York, United States of America.
Hasit MehtaDivision of Neuroradiology, Department of Radiology, Westchester Medical Center, Valhalla, New York, United States of America.
Fawaz Al-MuftiDepartment of Neurology, Westchester Medical Center, Valhalla, New York, United States of America.
Andrew McClellandDivision of Neuroradiology, Department of Radiology, Montefiore Medical Center, Bronx, New York, United States of America.
Edwin GulkoDivision of Neuroradiology, Department of Radiology, Westchester Medical Center, Valhalla, New York, United States of America. Electronic address: Edwin.Gulko@wmchealth.org.
Westchester Medical Center · USNew York Medical College · USMontefiore Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNumerous case reports and case series have described brain Magnetic Resonance Imaging (MRI) findings in Coronavirus disease 2019 (COVID-19) patients with concurrent posterior reversible encephalopathy syndrome (PRES). PURPOSE: We aim to compile and analyze brain MRI findings in patients with COVID-19 disease and PRES.

methodsPubMed and Embase were searched on April 5th, 2021 using the terms "COVID-19", "PRES", "SARS-CoV-2" for peer-reviewed publications describing brain MRI findings in patients 21 years of age or older with evidence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and PRES.

resultsTwenty manuscripts were included in the analysis, which included descriptions of 30 patients. The average age was 57 years old. Twenty-four patients (80%) required mechanical ventilation. On brain MRI examinations, 15 (50%) and 7 (23%) of patients exhibited superimposed foci of hemorrhage and restricted diffusion respectively.

conclusionsPRES is a potential neurological complication of COVID-19 related disease. COVID-19 patients with PRES may exhibit similar to mildly greater rates of superimposed hemorrhage compared to non-COVID-19 PRES patients.

Indexed as

COVID-19Posterior Leukoencephalopathy SyndromeBrainHumansMagnetic Resonance ImagingMiddle AgedSARS-CoV-2COVID-19MRI brainPRES

Identifiers

PMID34700172
PMCPMC8519663
OpenAlexW3205965923

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.