Evidence map›Paper›PMID 34708024›Full record

ReviewFrontiers in bioengineering and biotechnology2021

Advancing Discovery of Snail Mucins Function and Application.

Maxwell McDermott, Antonio R Cerullo, James Parziale, Eleonora Achrak, Sharmin Sultana, Jennifer Ferd, Safiyah Samad, William Deng, Adam B Braunschweig, Mandë Holford

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. Pooled it
  2. LiposomalInternational journal of molecular sciences · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Applications of a continuum model for brush gels.International journal of solids and structures · 2026
    Article
  8. Article
  9. Review
  10. Chemical Variability and Biological Potential ofMolecules (Basel, Switzerland) · 2025
    Review
  11. Article
  12. Article
  13. Synergistic Antibacterial Effect of Mucus Fraction fromAntibiotics (Basel, Switzerland) · 2025
    Article
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Heliyon · 2024
    Article
  20. Beyond the shell: malacology in medical dermatology.Archives of dermatological research · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Maxwell McDermottDepartment of Chemistry and Biochemistry, Hunter College, New York, NY, United States.
Antonio R CerulloDepartment of Chemistry and Biochemistry, Hunter College, New York, NY, United States.
James ParzialeDepartment of Chemistry and Biochemistry, Hunter College, New York, NY, United States.
Eleonora AchrakDepartment of Chemistry and Biochemistry, Hunter College, New York, NY, United States.
Sharmin SultanaDepartment of Chemistry and Biochemistry, Hunter College, New York, NY, United States.
Jennifer FerdDepartment of Chemistry and Biochemistry, Hunter College, New York, NY, United States.
Safiyah SamadDepartment of Chemistry and Biochemistry, Hunter College, New York, NY, United States.
William DengDepartment of Chemistry and Biochemistry, Hunter College, New York, NY, United States.
Adam B BraunschweigDepartment of Chemistry and Biochemistry, Hunter College, New York, NY, United States.
Mandë HolfordDepartment of Chemistry and Biochemistry, Hunter College, New York, NY, United States.
Hunter College · USCity University of New York · US

Funding

Training Program in Biomedical Imaging and Information SciencesT32EB009384 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI GEE, JAMES C, IVES, ZACHARY · 2009 to 2023
$4.0M
NIBIB NIH HHS T32 EB009384
6 · The paper itself

Abstract

Mucins are a highly glycosylated protein family that are secreted by animals for adhesion, hydration, lubrication, and other functions. Despite their ubiquity, animal mucins are largely uncharacterized. Snails produce mucin proteins in their mucous for a wide array of biological functions, including microbial protection, adhesion and lubrication. Recently, snail mucins have also become a lucrative source of innovation with wide ranging applications across chemistry, biology, biotechnology, and biomedicine. Specifically, snail mucuses have been applied as skin care products, wound healing agents, surgical glues, and to combat gastric ulcers. Recent advances in integrated omics (genomic, transcriptomic, proteomic, glycomic) technologies have improved the characterization of gastropod mucins, increasing the generation of novel biomaterials. This perspective describes the current research on secreted snail mucus, highlighting the potential of this biopolymer, and also outlines a research strategy to fulfill the unmet need of examining the hierarchical structures that lead to the enormous biological and chemical diversity of snail mucus genes.

Indexed as

biopolymerbiotechnologycosmeticsmucinsmucussnails

Identifiers

PMID34708024
PMCPMC8542881
OpenAlexW3207193191

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.