Evidence map›Paper›PMID 34713231›Full record

ReviewFrontiers in genome editing2020

CRISPR-Based Genetic Manipulation of

Deeva Uthayakumar, Jehoshua Sharma, Lauren Wensing, Rebecca S Shapiro

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in genome editing, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. EditingBiomolecules · 2026
    Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Early-Onset Candidemia in Adult Intensive Care Units.Diagnostics (Basel, Switzerland) · 2025
    Review
  11. Candida albicans: the current status regarding vaginal infections.Applied microbiology and biotechnology · 2025
    Review
  12. A comparative evaluation of CRISPR-Cas9 allele editing systems inbioRxiv : the preprint server for biology · 2025
    Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Deeva UthayakumarDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.
Jehoshua SharmaDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.
Lauren WensingDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.
Rebecca S ShapiroDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, ON, Canada.
University of Guelph · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The

Indexed as

biotechnologyCandidaCRISPRdrug discoveryfunctional genomicsfungal geneticsgene editingpathogenesis

Identifiers

PMID34713231
PMCPMC8525362
OpenAlexW3120511704

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.