Evidence map›Paper›PMID 34717725›Full record

ReviewDiabetology & metabolic syndrome2021

Impact of diabetes mellitus developing after kidney transplantation on patient mortality and graft survival: a meta-analysis of adjusted data.

Hailing Lin, Jiqiang Yan, Lei Yuan, Beibei Qi, Zhujing Zhang, Wanlu Zhang, Aihua Ma, Fuwan Ding

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Diabetology & metabolic syndrome, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 36 citations in OpenAlex.

  1. Prognostic impact of post-transplant diabetes mellitus in kidney allograft recipients: a meta-analysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
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  5. Impact of Early Post-Transplantation Diabetes Mellitus and Changes in Diabetic Status on Graft Failure and Mortality in Kidney Transplant Recipients.Transplant international : official journal of the European Society for Organ Transplantation · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Hailing Lin *Department of Endocrinology, The Yancheng School of Clinical Medicine of Nanjing Medical University, Yancheng Third People's Hospital, No. 75 Juchang Road, Yancheng, Jiangsu, China.
Jiqiang Yan *Department of Endocrinology, The Yancheng School of Clinical Medicine of Nanjing Medical University, Yancheng Third People's Hospital, No. 75 Juchang Road, Yancheng, Jiangsu, China.
Lei YuanDepartment of Endocrinology, The Yancheng School of Clinical Medicine of Nanjing Medical University, Yancheng Third People's Hospital, No. 75 Juchang Road, Yancheng, Jiangsu, China.
Beibei QiDepartment of Endocrinology, The Yancheng School of Clinical Medicine of Nanjing Medical University, Yancheng Third People's Hospital, No. 75 Juchang Road, Yancheng, Jiangsu, China.
Zhujing ZhangDepartment of Endocrinology, The Yancheng School of Clinical Medicine of Nanjing Medical University, Yancheng Third People's Hospital, No. 75 Juchang Road, Yancheng, Jiangsu, China.
Wanlu ZhangDepartment of Endocrinology, The Yancheng School of Clinical Medicine of Nanjing Medical University, Yancheng Third People's Hospital, No. 75 Juchang Road, Yancheng, Jiangsu, China.
Aihua MaDepartment of Endocrinology, The Yancheng School of Clinical Medicine of Nanjing Medical University, Yancheng Third People's Hospital, No. 75 Juchang Road, Yancheng, Jiangsu, China.
Fuwan DingDepartment of Endocrinology, The Yancheng School of Clinical Medicine of Nanjing Medical University, Yancheng Third People's Hospital, No. 75 Juchang Road, Yancheng, Jiangsu, China. sunlcs@163.com.ORCID http://orcid.org/0000-0003-0114-0315
Yancheng Third People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPost-transplant diabetes mellitus (PTDM) occurs in 10-30% of kidney transplant recipients. However, its impact on mortality and graft survival is still ambiguous. Therefore, the current study aimed to analyze if PTDM increases mortality and graft failure by pooling multivariable-adjusted data from individual studies.

methodsPubMed, Embase, and CENTRAL, and Google Scholar were searched for studies comparing mortality and graft failure between PTDM and non-diabetic patients. Multivariable-adjusted hazard ratios (HR) were pooled in a random-effects model.

resultsFourteen retrospective studies comparing 9872 PTDM patients with 65,327 non-diabetics were included. On pooled analysis, we noted a statistically significant increase in the risk of all-cause mortality in patients with PTDM as compared to non-diabetics (HR: 1.67 95% CI 1.43, 1.94 I

conclusionKidney transplant patients developing PTDM have a 67% increased risk of all-cause mortality and a 35% increased risk of graft failure. Further studies are needed to determine the exact cause of increased mortality and the mechanism involved in graft failure.

Indexed as

Diabetes mellitusGraft failureMortalityOrgan transplantRenal allograft

Identifiers

PMID34717725
PMCPMC8557540
OpenAlexW3210479995

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.