Evidence mapPaperPMID 34718757Full record

ReviewNephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association2021

Cognitive disorders in patients with chronic kidney disease: specificities of clinical assessment.

Marion Pépin, Ana Carina Ferreira, Mustafa Arici, Maie Bachman, Michelangela Barbieri, Inga Arune Bumblyte, Sol Carriazo, Pilar Delgado, Liliana Garneata, Konstantinos Giannakou and 14 more

Erratum issuedOpen access · bronzeAbstract readReview
In one paragraph

Review in Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Article
  7. Cognitive Impairment Predicts Adverse Outcomes in CKD.Kidney international reports · 2026
    Article
  8. Article
  9. Observational
  10. Review
  11. Observational
  12. Cholinergic system in patients with chronic kidney disease: cognitive and renal implications.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Review
  13. Article
  14. Diagnosis and Management of Dementia for the Nephrology Clinician: A Review.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2025
    Review
  15. Article
  16. Article
  17. Article
  18. Observational
  19. CONNECT: what has been done and what needs to be done.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Article
  20. Chemotherapy-related cognitive impairment and kidney dysfunction.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

24 authors at 16 institutions in 12 countries.

Marion PépinParis-Saclay University, UVSQ, Inserm, Clinical Epidemiology Team, Centre de Recherche en Epidémiologie et Santé des Populations (CESP), Villejuif, France.
Ana Carina FerreiraDepartment of Nephrology, Centro Hospitalar e Universitário de Lisboa Central-Hospital Curry Cabral, Lisbon, Portugal.ORCID 0000-0002-1323-5293
Mustafa AriciDepartment of Internal Medicine, Division of Nephrology, Faculty of Medicine, Hacetepe University, Ankara, Turkey.
Maie BachmanDepartment of Health Technologies, School of Information Technologies, Tallinn University of Technology, Tallinn, Estonia.
Michelangela BarbieriDepartment of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy.
Inga Arune BumblyteDepartment of Nephrology, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Sol CarriazoDepartment of Nephrology and Hypertension, IIS-Fundacion Jimenez Diaz UAM, Madrid, Spain.ORCID 0000-0002-6697-5279
Pilar DelgadoDepartment of Neurology, Vall d'Hebron Hospital, Universitat Autonoma de Barcelona, Barcelona, Spain.
Liliana GarneataDepartment of Internal Medicine and Nephrology, "Carol Davila" University of Medicine and Pharmacy, "Dr Carol Davila" Teaching Hospital of Nephrology, Bucharest, Romania.
Konstantinos GiannakouDepartment of Health Sciences, School of Sciences, European University Cyprus, Nicosia, Cyprus.
Olivier GodefroyDepartment of Neurology, Amiens University Hospital, and Laboratory of Functional Neurosciences (UR UPJV 4559), Jules Verne University of Picardie, Amiens, France.
Tomasz GrodzickiDepartment of Internal Medicine and Gerontology, Jagiellonian University Medical College, Cracow, Poland.ORCID 0000-0003-0159-4915
Aleksandra Klimkowicz-MrowiecDepartment of Internal Medicine and Gerontology, Jagiellonian University Medical College, Cracow, Poland.
Justina KurganaiteDepartment of Nephrology, Lithuanian University of Health Sciences, Kaunas, Lithuania.ORCID 0000-0003-2385-5346
Sophie LiabeufDepartment of Pharmacology, Amiens University Medical Center, Amiens, France.ORCID 0000-0001-5384-9006
Carmen Antonia MocanuDepartment of Internal Medicine and Nephrology, "Carol Davila" University of Medicine and Pharmacy, "Dr Carol Davila" Teaching Hospital of Nephrology, Bucharest, Romania.
Giuseppe PaolissoDepartment of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy.
Goce SpasovskiDepartment of Nephrology, Clinical Centre "Mother Theresa", Saints Cyril and Methodius University, Skopje, North Macedonia.
Evgueniy Stefanov VazelovDialysis Clinic of UMHAT "Alexandrovska", Sofia Medical University, Sofia, Bulgaria.
Davide ViggianoDepartment of Nephrology, University of Campania "Luigi Vanvitelli", Naples; BIOGEM, Ariano Irpino, Italy.
Carmine ZoccaliRenal Research Institute, New York, NY, USA.ORCID 0000-0002-6616-1996
Ziad A MassyParis-Saclay University, UVSQ, Inserm, Clinical Epidemiology Team, Centre de Recherche en Epidémiologie et Santé des Populations (CESP), Villejuif, France.
Andrzej WięcekDepartment of Nephrology, Transplantation and Internal Medicine, Medical University of Silesia, Katowice, Poland.
CONNECT Action (Cognitive Decline in Nephro-Neurology European Cooperative Target)
University of Campania "Luigi Vanvitelli" · ITInserm · FRLithuanian University of Health Sciences · LTCarol Davila University of Medicine and Pharmacy · ROJagiellonian University · PLEuropean University Cyprus · CYHospital Curry Cabral · PTHospital Universitario Fundación Jiménez Díaz · ESLaboratoire de neurosciences fonctionnelles et pathologies · FRRenal Research Institute · USSs. Cyril and Methodius University in Skopje · MKUniversitat Autònoma de Barcelona · ESHacettepe University · TRMedical University of Silesia · PLTallinn University of Technology · EECentre Hospitalier Universitaire Amiens-Picardie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurocognitive disorders are frequent among chronic kidney disease (CKD) patients. Identifying and characterizing cognitive impairment (CI) can help to assess the ability of adherence to CKD risk reduction strategy, identify potentially reversible causes of cognitive decline, modify pharmacotherapy, educate the patient and caregiver and provide appropriate patient and caregiver support. Numerous factors are associated with the development and progression of CI in CKD patients and various conditions can influence the results of cognitive assessment in these patients. Here we review clinical warning signs that should lead to cognitive screening; conditions frequent in CKD at risk to interfere with cognitive testing or performance, including specificities of cognitive assessment in dialysis patients or after kidney transplantation; and available tests for screening and observed cognitive patterns in CKD patients.

Indexed as

Cognition DisordersRenal Insufficiency, ChronicCognitionHumansNeuropsychological TestsRenal Dialysischronic kidney diseaseclinical assessmentcognitive impairmentcognitive screening testcomprehensive battery

Identifiers

PMID34718757
PMCPMC8713156
OpenAlexW3209927131

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.