Evidence map›Paper›PMID 34719237›Full record

ArticleHypertension (Dallas, Tex. : 1979)2021

Elastin-Like Polypeptide: VEGF-B Fusion Protein for Treatment of Preeclampsia.

Jamarius P Waller, John Aaron Howell, Hali Peterson, Eric M George, Gene L Bidwell

Open access · bronzeAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jamarius P WallerFrom the Department of Pharmacology and Toxicology (J.P.W., G.L.B.), University of Mississippi Medical Center, Jackson, MS.ORCID 0000-0002-4714-0030
John Aaron HowellDepartment of Neurology (J.A.H., G.L.B.), University of Mississippi Medical Center, Jackson, MS.ORCID 0000-0001-9875-6022
Hali PetersonDepartment of Medicine (H.P.), University of Mississippi Medical Center, Jackson, MS.
Eric M GeorgeDepartment of Physiology (E.M.G.), University of Mississippi Medical Center, Jackson, MS.ORCID 0000-0002-6622-7369
Gene L BidwellFrom the Department of Pharmacology and Toxicology (J.P.W., G.L.B.), University of Mississippi Medical Center, Jackson, MS.ORCID 0000-0001-9104-150X
University of Mississippi Medical Center · US

Funding

STRUCTURAL VASCULAR ADAPTATION OF THE MICROCIRCULATIONP01HL051971 · NHLBI · UNIVERSITY OF MISSISSIPPI MEDICAL CENTER · PI RECKELHOFF, JANE F · 1993 to 2018
$39.4M
The role of leptin in autoimmune-associated hypertensionP20GM104357 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI HALL, JOHN E · 2013 to 2022
$23.4M
A Novel Protein Delivery System for Therapy of PreeclampsiaR01HL121527 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI BIDWELL, GENE LEFLORE · 2014 to 2023
$4.1M
A Novel Therapy For PreeclampsiaR01HL137791 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI GEORGE, ERIC MATTHEW · 2017 to 2021
$1.9M
The use of a biopolymer-fused form of VEGF-B for the treatment of Preeclampsia.F31HL151180 · NHLBI · UNIVERSITY OF MISSISSIPPI MED CTR · PI WALLER, JAMARIUS · 2020 to 2022
$86k
NHLBI NIH HHS F31 HL151180NHLBI NIH HHS P01 HL051971NHLBI NIH HHS R01 HL121527NHLBI NIH HHS R01 HL137791NIGMS NIH HHS P20 GM104357
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

AnimalsDisease Models, AnimalElastinEndothelial CellsFemaleHumansPre-EclampsiaPregnancyRatsRats, Sprague-DawleyTreatment OutcomeVascular Endothelial Growth Factor BElastinELN protein, humanVascular Endothelial Growth Factor Bblood pressuredrug developmentinflammationplasmapregnancy

Identifiers

PMID34719237
PMCPMC8585700
OpenAlexW3209280252

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.