Evidence map›Paper›PMID 34722260›Full record

ArticleFrontiers in oncology2021

Shahid M Baba, Arshad A Pandith, Zafar A Shah, Sajad A Geelani, Javid R Bhat, Ayaz Gul, Sameer A Guru, Hamed A El-Serehy, Abid M Koul, Sheikh Mansoor

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 3 countries.

Shahid M BabaDepartment of Immunology and Molecular Medicine, Sher-i-Kashmir Institute of Medical Sciences (SKIMS), Srinagar, India.
Arshad A PandithAdvanced Centre for Human Genetics, SKIMS, Srinagar, India.
Zafar A ShahDepartment of Immunology and Molecular Medicine, Sher-i-Kashmir Institute of Medical Sciences (SKIMS), Srinagar, India.
Sajad A GeelaniDepartment of Clinical Hematology, SKIMS, Srinagar, India.
Javid R BhatAdvanced Centre for Human Genetics, SKIMS, Srinagar, India.
Ayaz GulDepartment of Immunology and Molecular Medicine, Sher-i-Kashmir Institute of Medical Sciences (SKIMS), Srinagar, India.
Sameer A GuruDepartment of Developmental and System Biology, Lurie Children's Hospital Northwest University, Chicago, IL, United States.
Hamed A El-SerehyDepartment of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia.
Abid M KoulAdvanced Centre for Human Genetics, SKIMS, Srinagar, India.
Sheikh MansoorAdvanced Centre for Human Genetics, SKIMS, Srinagar, India.
Sher-i-Kashmir Institute of Medical Sciences · INKing Saud University · SANorthwest University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionGlutathione S-transferase (GST) gene deletion or polymorphic sequence variations lead to decreased enzyme activity that influences susceptibility and response to chemotherapy in acute lymphoblastic leukemia (ALL). This case-control study investigated the association of GST gene polymorphisms with the etiology and therapeutic outcome of B-ALL among Kashmiri population.

methodsA total of 300 individuals including 150 newly diagnosed B-ALL patients and an equal number of age and gender matched controls were genotyped for five GST gene polymorphisms by polymerase chain reaction-restriction fragment length polymorphism technique (PCR-RFLP) and multiplex PCR techniques.

resultsHigher frequency of

conclusionThis study demonstrated that

Indexed as

acute lymphoblastic leukemiaglutathione S-transferaseGSTO1GSTO2KashmirPCR-RFLPpolymorphismsurvival analysis

Identifiers

PMID34722260
PMCPMC8552530
OpenAlexW3207431776

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.