Evidence map›Paper›PMID 34724866›Full record

ArticleBioengineered2021

LIM domain-containing 2 (LIMD2) promotes the progress of ovarian cancer via the focal adhesion signaling pathway.

Lixin Chen, Ji Qian, Qinghua You, Jie Ma

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Lixin ChenSchool of Pharmaceutical Sciences, Jilin University, Changchun, Jilin, China.
Ji QianBio-teq Center, Fudan University, Shanghai, China.
Qinghua YouDepartment of Pathology, Shanghai Pudong Hospital, Shanghai, China.
Jie MaSchool of Pharmaceutical Sciences, Jilin University, Changchun, Jilin, China.
Jilin University · CNFudan University · CNPudong Medical Center · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian cancer (OC) is the leading cause of death from gynecological cancer. In this study, we aimed to explore the role and potential mechanism of LIMD2 during the progression of OC. The expression of LIMD2 was analyzed by GEPIA (Gene Expression Profiling Interactive Analysis) database. Western blot and real-time PCR were applied to detect the gene expression of

Indexed as

Disease ProgressionSignal TransductionAnimalsCarcinogenesisCell Line, TumorCell MovementCell ProliferationFemaleFocal AdhesionsGene Expression ProfilingGene Expression Regulation, NeoplasticGene Knockdown TechniquesHumansMiceMice, NudeNeoplasm MetastasisLIMD2 protein, humanNeoplasm Proteinsfocal adhesionLIMD2Ovarian cancerprogress

Identifiers

PMID34724866
PMCPMC8809939
OpenAlexW3211103141

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.