ArticleESC heart failure2021
Left atrial structural and mechanical remodelling in heart failure with reduced ejection fraction.
Article in ESC heart failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic Value of Left Atrial Strain in Heart Failure: A Systematic Review and Meta-Analysis.Frontiers in cardiovascular medicine · 2022Pooled it
- Etiology-Related Differences in Left Ventricular Remodeling and Left Atrial Function in Patients with Heart Failure and Reduced Ejection Fraction Referred for ICD/CRT Implantation.Journal of clinical medicine · 2026Article
- Prognostic Relevance of Speckle Tracking-Derived Biatrial Stiffness Index in Patients with Dilated Cardiomyopathy.Journal of clinical medicine · 2026Article
- Beyond Conventional Echocardiography: The Emerging Role of Left Atrioventricular Coupling Indexes in Chronic Chagas Disease.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Combined Left Ventricular and Left Atrial Strain Assessment for Long-Term Risk Stratification in Heart Failure With Reduced Ejection Fraction.Echocardiography (Mount Kisco, N.Y.) · 2026Article
- Quantitative evaluation of left atrial function via two-dimensional speckle-tracking echocardiography in patients with different grades of hypertension.Quantitative imaging in medicine and surgery · 2026Article
- Role of imaging techniques in monitoring atrial cardiomyopathy and atrial failure: a scientific statement.ESC heart failure · 2026Review
- Left atrial strain and all-cause mortality in patients with heart failure with reduced ejection fraction: a retrospective cohort study.BMJ open · 2026Article
- Left Atrial Dysfunction in Patients with Atrial Fibrillation and Heart Failure.Current cardiology reports · 2025Review
- Peak atrial longitudinal strain as a predictor of postoperative atrial fibrillation in isolated coronary artery bypass grafting: Insights from a single-centre study in Indonesia.Global cardiology science & practice · 2025Article
- Impact of catheter ablation on atrial fibrillation outcomes in various cardiomyopathies: findings from LGE-MRI quantified atrial fibrosis analysis.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2025Article
- Association of breastfeeding duration with cardiac structure and function in 4 years old.European journal of clinical nutrition · 2025Article
- Article
- Prognostic value of left atrial reverse remodelling in patients hospitalized with acute decompensated heart failure.ESC heart failure · 2024Article
- Lone Giant Atrium as a Variant of Atrial Cardiomyopathy: A Cardiovascular Magnetic Resonance Imaging Case Series.Journal of cardiovascular development and disease · 2024Article
- Prognostic value of temporal patterns of left atrial reservoir strain in patients with heart failure with reduced ejection fraction.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Observational
- A normal and particularly small (<35 mm) left atrial size measured during echocardiography suggests low likelihood of moderate or severe left ventricular systolic dysfunction.American journal of cardiovascular disease · 2024Article
- Decreased Peak Left Atrial Longitudinal Strain Is Associated with Persistent Pulmonary Hypertension Associated with Left Heart Disease.Journal of clinical medicine · 2022Article
- The Added Value of Atrial Strain Assessment in Clinical Practice.Diagnostics (Basel, Switzerland) · 2022Review
- The loss of left atrial contractile function predicts a worse outcome in HFrEF patients.Frontiers in cardiovascular medicine · 2022Article
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsIn patients with heart failure with reduced ejection fraction (HFrEF), an association between left atrial (LA) dilatation and dysfunction is expected, but the degree of coexistence of the two abnormalities and their relative prognostic role is not known. METHODS AND
resultsA total of 626 HFrEF patients formed the study population. All of them underwent a comprehensive echocardiographic evaluation. LA maximal volume was indexed to body surface area (LAVi); LA function was assessed using strain analysis during the reservoir phase: peak atrial longitudinal strain (PALS) analysis. Study primary endpoint was overall mortality or hospitalization for worsening heart failure. Four groups of patients were included in this study according to LAVi (≤34 or >34 mL/m
conclusionsLeft atrial dilatation and dysfunction frequently but not invariably coexist. PALS emerged as a significant prognostic parameter in HFrEF even in the absence of LA dilation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.