Evidence map›Paper›PMID 34727009›Full record

ArticleRedox report : communications in free radical research2021

Vitamin D levels and oxidative stress markers in patients hospitalized with COVID-19.

Emilija Atanasovska, Marija Petrusevska, Dragica Zendelovska, Katerina Spasovska, Milena Stevanovikj, Katerina Kasapinova, Kalina Gjorgjievska, Nikola Labachevski

Open access · goldAbstract read
In one paragraph

Article in Redox report : communications in free radical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Emilija AtanasovskaFaculty of Medicine, University of Ss Cyril and Methodius, Institute of Preclinical and Clinical Pharmacology and Toxicology, Skopje, Republic of North Macedonia.ORCID 0000-0003-4596-9563
Marija PetrusevskaFaculty of Medicine, University of Ss Cyril and Methodius, Institute of Preclinical and Clinical Pharmacology and Toxicology, Skopje, Republic of North Macedonia.ORCID 0000-0002-3785-1285
Dragica ZendelovskaFaculty of Medicine, University of Ss Cyril and Methodius, Institute of Preclinical and Clinical Pharmacology and Toxicology, Skopje, Republic of North Macedonia.ORCID 0000-0003-4675-6340
Katerina SpasovskaIntensive Care Unit, University Clinic for Infectious Diseases and Febrile Conditions, Skopje, Republic of North Macedonia.ORCID 0000-0002-4614-9842
Milena StevanovikjIntensive Care Unit, University Clinic for Infectious Diseases and Febrile Conditions, Skopje, Republic of North Macedonia.
Katerina KasapinovaIntensive Care Unit, University Surgery Clinic 'St.Naum Ohridski', Skopje, Republic of North Macedonia.
Kalina GjorgjievskaFaculty of Medicine, University of Ss Cyril and Methodius, Institute of Preclinical and Clinical Pharmacology and Toxicology, Skopje, Republic of North Macedonia.ORCID 0000-0001-5750-4398
Nikola LabachevskiFaculty of Medicine, University of Ss Cyril and Methodius, Institute of Preclinical and Clinical Pharmacology and Toxicology, Skopje, Republic of North Macedonia.
Ss. Cyril and Methodius University in Skopje · MKUniversity Clinic of Traumatology · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOVID-19 is characterized by the presence of oxidative stress. Vitamin D status has been reviewed as one of the factors that may affect disease severity. The aim of this study was to assess the relationship between serum vitamin D levels, oxidative stress markers and disease severity in hospitalized COVID-19 patients.

methodsVitamin D levels were measured in 33 patients with COVID-19. The total antioxidant power and plasma peroxides were determined in serum.

resultsSevere COVID-19 patients have lower vitamin D levels (18.39 ± 2.29 ng/mL vs. 28.47 ± 3.05 ng/mL,

conclusionThe presented data provide a justification to consider vitamin D as an important factor that could ameliorate disease severity through its anti-inflammatory and antioxidant effects.

Indexed as

Oxidative StressAdultAgedAntioxidantsBiomarkersCOVID-19FemaleHospitalizationHumansMaleMiddle AgedRepublic of North MacedoniaVitamin DAntioxidantsBiomarkersVitamin DantioxidantsCOVID-19disease severityinflammationoxidative stressplasma peroxidesvitamin D

Identifiers

PMID34727009
PMCPMC8567917
OpenAlexW3209821344

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.