Evidence map›Paper›PMID 34728628›Full record

ArticleNature communications2021

N

Yanying Wang, Jing Wang, Xiaoyu Li, Xushen Xiong, Jianyi Wang, Ziheng Zhou, Xiaoxiao Zhu, Yang Gu, Dan Dominissini, Lei He and 3 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 169 papers.

0numbers the graph read from it
0cells of the map it votes in
169citing papers in PubMed
13.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

169 citing papers in PubMed, 249 citations in OpenAlex.

  1. Cotinine Promotes Cancer Cell Proliferation and mEnvironment & health (Washington, D.C.) · 2026
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  9. mCell death & disease · 2026
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  12. TRMT6-directed mNPJ precision oncology · 2026
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  14. tRNA mCellular & molecular immunology · 2026
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  15. Review
  16. mAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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  17. Article
  18. Review
  19. Review
  20. TRMT6/TRMT61A-mediated tRNA mCellular & molecular biology letters · 2026
    Article

109 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Yanying Wang *CAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China. wangyanying@moon.ibp.ac.cn.
Jing Wang *CAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China.
Xiaoyu Li *State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China.
Xushen Xiong *State Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China.
Jianyi WangCAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China.
Ziheng ZhouCAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China.
Xiaoxiao ZhuCAS Key Laboratory of RNA Biology; Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China.
Yang GuCAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China.
Dan DominissiniCancer Research Center and Wohl Institute for Translational Medicine, Chaim Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, 6997801, Tel Aviv, Israel.
Lei HeDepartment of Hepatobiliary Surgery, PLA General Hospital, 100853, Beijing, China.
Yong TianCAS Key Laboratory of RNA Biology; Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China. ytian@ibp.ac.cn.ORCID 0000-0002-8790-1148
Chengqi YiState Key Laboratory of Protein and Plant Gene Research, School of Life Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China. chengqi.yi@pku.edu.cn.ORCID 0000-0003-2540-9729
Zusen FanCAS Key Laboratory of Infection and Immunity, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China. fanz@moon.ibp.ac.cn.ORCID 0000-0002-7866-8217
Chinese Academy of Sciences · CNPeking University · CNChinese PLA General Hospital · CNInstitute of Biophysics · CNTel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) accounts for the majority of primary liver cancers and is characterized by high recurrence and heterogeneity, yet its mechanism is not well understood. Here we show that N

Indexed as

AdenosineAnimalsCarcinoma, HepatocellularCell Line, TumorCell Self RenewalCholesterolDisease Models, AnimalFemaleHumansLiver NeoplasmsMaleMembrane ProteinsMethylationMiceMice, Inbred C57BLMice, Knockout1-methyladenosineAdenosineCholesterolCRLS1 protein, humanMembrane ProteinsPPAR gammaPPARG protein, humanRNA, TransferTRMT61A protein, humantRNA Methyltransferases

Identifiers

PMID34728628
PMCPMC8563902
OpenAlexW3208877024

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.