Evidence map›Paper›PMID 34733272›Full record

ArticleFrontiers in immunology2021

Integrative Characterization of the Role of IL27 In Melanoma Using Bioinformatics Analysis.

Chunyu Dong, Dan Dang, Xuesong Zhao, Yuanyuan Wang, Zhijun Wang, Chuan Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 47 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Chunyu DongDepartment of Pediatric Surgery, The First Hospital of Jilin University, Changchun, China.
Dan DangDepartment of Neonatology, The First Hospital of Jilin University, Changchun, China.
Xuesong ZhaoDepartment of Pediatric Surgery, The First Hospital of Jilin University, Changchun, China.
Yuanyuan WangDepartment of Pediatric Ultrasound, The First Hospital of Jilin University, Changchun, China.
Zhijun WangDepartment of Pediatric Surgery, The First Hospital of Jilin University, Changchun, China.
Chuan ZhangDepartment of Pediatric Surgery, The First Hospital of Jilin University, Changchun, China.
Jilin University · CNFirst Hospital of Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: RNA-seq data, drug sensitivity data, and clinical data were obtained from TCGA, GEO, CCLE, and CTRP. Log-rank test was used to determine the survival value of Results: Clinically, Conclusions:

Indexed as

Computational BiologyDisease SusceptibilityBiomarkersCombined Modality TherapyDatabases, GeneticDisease ManagementGene Expression ProfilingGene Expression Regulation, NeoplasticHumansInterleukin-27MelanomaMolecular Sequence AnnotationPrognosisSurvival AnalysisTreatment OutcomeBiomarkersInterleukin-27CD8+ T cellsIL27immunotherapymelanomatumor microenvironmentβ-catenin

Identifiers

PMID34733272
PMCPMC8558420
OpenAlexW3207581726

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.