Evidence mapPaperPMID 34735601Full record

SynthesisSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2022

The efficacy of web or mobile-based interventions to alleviate emotional symptoms in people with advanced cancer: a systematic review and meta-analysis.

Vijayvardhan Kamalumpundi, Seyedehtanaz Saeidzadeh, Nai-Ching Chi, Rajeshwari Nair, Stephanie Gilbertson-White

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 5 pooled it
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 5 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Role of Digital Health on Palliative Care: Umbrella Review.Journal of medical Internet research · 2025
    Pooled it
  2. Pooled it
  3. Effectiveness of ePRO-based symptom management for cancer patients: a systematic review and meta-analysis of randomized controlled studies.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  4. Effect of applying digital health in palliative care for patients with advanced cancer: a meta-analysis and systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  5. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Vijayvardhan KamalumpundiDepartment of Internal Medicine, University of Iowa Carver College of Medicine, Newton Road, Iowa City, IA, 52242, USA.
Seyedehtanaz SaeidzadehSchool of Nursing, University of Wisconsin-Madison, Madison, WI, USA.
Nai-Ching ChiCollege of Nursing, University of Iowa, Iowa City, IA, USA.
Rajeshwari NairDepartment of Internal Medicine, University of Iowa Carver College of Medicine, Newton Road, Iowa City, IA, 52242, USA.
Stephanie Gilbertson-WhiteCollege of Nursing, University of Iowa, Iowa City, IA, USA. stephanie-gilbertson-white@uiowa.edu.ORCID http://orcid.org/0000-0002-9718-3717
University of Iowa · USUniversity of Wisconsin–Madison · US

Funding

Viral VectorP30CA086862 · UNIVERSITY OF IOWA · 2000 to 2025
$11.9M
6 · The paper itself

Abstract

purposeThis review aims to critically evaluate the efficacy of web or mobile-based (WMB) interventions impacting emotional symptoms in patients with advanced cancer.

methodArticles published from 1991 to 2019 were identified using PubMed, PsycINFO, CINAHL, and Scopus. Only interventions involving adults with advanced cancer using a WMB intervention to manage emotional symptoms were included. Risk of bias was assessed using ROBINS-I and ROB2 tools. Studies that reported mean symptom scores were pooled using a random-effects model, and standardized mean difference (SMD) and 95% CIs were calculated.

resultsTwenty-three of the 1177 screened studies met the inclusion criteria, and a total sample of 2558 patients were included. The sample was 57% female, and 33% had advanced cancer with mean age of 57.15 years. Thirteen studies evaluated anxiety, nineteen evaluated depression, and eleven evaluated distress. Intervention components included general information, tracking, communication, multimedia choice, interactive online activities, tailoring/feedback, symptom management support content, and self-monitoring. Overall pooled results showed that WMB interventions' effects on decreasing anxiety (SMD - 0.20, - 0.45 to 0.05, I

conclusionThis meta-analysis demonstrated that WMB interventions were not efficacious in alleviating emotional symptoms in adults with advanced cancer. Considering the diversity of interventions, the efficacy of WMB interventions and its impacts on emotional symptoms should be further explored.

Indexed as

AnxietyNeoplasmsAdultFemaleHumansMaleMiddle AgedPalliative CareQuality of LifeAdvanced cancerEmotional symptomsMeta-analysisSymptom managementSystematic reviewWeb application

Identifiers

PMID34735601
OpenAlexW3210835201

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.