Evidence map›Paper›PMID 34737972›Full record

ArticleFrontiers in cellular and infection microbiology2021

Longitudinal Analysis of the Intestinal Microbiota in the Obese Mangalica Pig Reveals Alterations in Bacteria and Bacteriophage Populations Associated With Changes in Body Composition and Diet.

Haley A Hallowell, Keah V Higgins, Morgan Roberts, Robert M Johnson, Jenna Bayne, Herris Stevens Maxwell, Terry Brandebourg, Elizabeth Hiltbold Schwartz

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 11 citations in OpenAlex.

  1. Alternating High-Fat and Polysaccharide Diets Modulates Gut Phage-Bacterial Interplay.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Secondary bile acids are associated with body lipid accumulation in obese pigs.Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2024
    Article
  6. Dietary Effects on the Gut Phageome.International journal of molecular sciences · 2024
    Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Haley A HallowellDepartment of Biological Sciences, Auburn University, College of Science and Mathematics, Auburn, AL, United States.
Keah V HigginsDepartment of Biological Sciences, Auburn University, College of Science and Mathematics, Auburn, AL, United States.
Morgan RobertsDepartment of Animal Sciences, College of Agriculture, Auburn University, Auburn, AL, United States.
Robert M JohnsonDepartment of Biological Sciences, Auburn University, College of Science and Mathematics, Auburn, AL, United States.
Jenna BayneDepartment of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.
Herris Stevens MaxwellDepartment of Clinical Sciences, College of Veterinary Medicine, Auburn University, Auburn, AL, United States.
Terry BrandebourgDepartment of Animal Sciences, College of Agriculture, Auburn University, Auburn, AL, United States.
Elizabeth Hiltbold SchwartzDepartment of Biological Sciences, Auburn University, College of Science and Mathematics, Auburn, AL, United States.
Auburn University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to its immunomodulatory potential, the intestinal microbiota has been implicated as a contributing factor in the development of the meta-inflammatory state that drives obesity-associated insulin resistance and type 2 diabetes. A better understanding of this link would facilitate the development of targeted treatments and therapies to treat the metabolic complications of obesity. To this end, we validated and utilized a novel swine model of obesity, the Mangalica pig, to characterize changes in the gut microbiota during the development of an obese phenotype, and in response to dietary differences. In the first study, we characterized the metabolic phenotype and gut microbiota in lean and obese adult Mangalica pigs. Obese or lean groups were created by allowing either

Indexed as

BacteriophagesDiabetes Mellitus, Type 2Gastrointestinal MicrobiomeAnimalsBacteriaBody CompositionDiet, High-FatObesitySwineagedietMangalicamicrobiotaobesityswine

Identifiers

PMID34737972
PMCPMC8560744
OpenAlexW3207626578

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.