Evidence map›Paper›PMID 34738093›Full record

ArticleLivers2021

Perfluoroalkyl Carboxylic Acids Interact with the Human Bile Acid Transporter NTCP.

Melissa J Ruggiero, Haley Miller, Jessica Y Idowu, Jeremiah D Zitzow, Shu-Ching Chang, Bruno Hagenbuch

Open access · goldAbstract read
In one paragraph

Article in Livers, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Effects of PFAS on human liver transporters: implications for health outcomes.Toxicological sciences : an official journal of the Society of Toxicology · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. New approach methodologies: A quantitative in vitro to in vivo extrapolation case study with PFASs.Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association · 2023
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Melissa J RuggieroDepartment of Pharmacology, Toxicology and Therapeutics, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
Haley MillerDepartment of Pharmacology, Toxicology and Therapeutics, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
Jessica Y IdowuDepartment of Pharmacology, Toxicology and Therapeutics, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
Jeremiah D ZitzowMedical Department, 3M Company, St Paul, MN 55144, USA.
Shu-Ching ChangMedical Department, 3M Company, St Paul, MN 55144, USA.
Bruno HagenbuchDepartment of Pharmacology, Toxicology and Therapeutics, The University of Kansas Medical Center, Kansas City, KS 66160, USA.
University of Kansas Medical Center · US3M (United States) · US

Funding

Nuclear Receptors in Liver Health and DiseaseP20GM103549 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI JAESCHKE, HARTMUT W. · 2012 to 2015
$8.1M
Pilot Grants ProgramP30GM118247 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI WEINMAN, STEVEN A · 2016 to 2020
$5.5M
Molecular Characterization of Hepatic Organic Anion Transporting PolypeptidesR01GM077336 · NIGMS · UNIVERSITY OF KANSAS MEDICAL CENTER · PI HAGENBUCH, BRUNO · 2007 to 2019
$3.7M
NIGMS NIH HHS P20 GM103549NIGMS NIH HHS P30 GM118247NIGMS NIH HHS R01 GM077336
6 · The paper itself

Abstract

Na

Indexed as

perfluoroalkyl acidsperfluoroalkyl carboxylatestaurocholate transport

Identifiers

PMID34738093
PMCPMC8562773
OpenAlexW3206980534

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.