Evidence map›Paper›PMID 34739818›Full record

ArticleCurrent biology : CB2021

Polarized Dishevelled dissolution and reassembly drives embryonic axis specification in sea star oocytes.

S Zachary Swartz, Tzer Han Tan, Margherita Perillo, Nikta Fakhri, Gary M Wessel, Athula H Wikramanayake, Iain M Cheeseman

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Current biology : CB, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  8. Live imaging of echinoderm embryos to illuminate evo-devo.Frontiers in cell and developmental biology · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

S Zachary SwartzWhitehead Institute for Biomedical Research, Cambridge, MA 02142, USA; Embryology Course: Concepts and Techniques in Modern Developmental Biology, Marine Biological Laboratory, Woods Hole, MA 02543, USA. Electronic address: szs@wi.mit.edu.
Tzer Han TanMassachusetts Institute of Technology, Department of Physics, Cambridge, MA 02142, USA.
Margherita PerilloMCB Department, Brown University, Providence, RI 02912, USA.
Nikta FakhriMassachusetts Institute of Technology, Department of Physics, Cambridge, MA 02142, USA.
Gary M WesselMCB Department, Brown University, Providence, RI 02912, USA.
Athula H WikramanayakeDepartment of Biology, University of Miami, Coral Gables, FL 33134, USA; Embryology Course: Concepts and Techniques in Modern Developmental Biology, Marine Biological Laboratory, Woods Hole, MA 02543, USA.
Iain M CheesemanWhitehead Institute for Biomedical Research, Cambridge, MA 02142, USA. Electronic address: icheese@wi.mit.edu.
Brown University · USMarine Biological Laboratory · USMassachusetts Institute of Technology · USWhitehead Institute for Biomedical Research · US

Funding

Molecular Analysis of Kinetochore FunctionR35GM126930 · NIGMS · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI Iain McPherson Cheeseman · 2018 to 2026
$7.0M
Embryology: Methods & Concepts in Modern Developmental BiologyR25HD094666 · NICHD · MARINE BIOLOGICAL LABORATORY · PI Linda E Hyman, Tatjana Piotrowski · 2018 to 2026
$1.3M
Molecular control of oocyte arrest, meiosis, and the transition to developmentK99HD099315 · NICHD · WHITEHEAD INSTITUTE FOR BIOMEDICAL RES · PI SWARTZ, STEVEN ZACHARY · 2019 to 2021
$328k
NICHD NIH HHS K99 HD099315NICHD NIH HHS R25 HD094666NIGMS NIH HHS R35 GM126930
6 · The paper itself

Abstract

The organismal body axes that are formed during embryogenesis are intimately linked to intrinsic asymmetries established at the cellular scale in oocytes.

Indexed as

Body PatterningStarfishAnimalsEmbryonic DevelopmentOocytesSolubilitybody axisDishevelledmeiosisoocytePatiria miniatapolaritysea starstarfishWnt

Identifiers

PMID34739818
PMCPMC8692449
OpenAlexW3204058394

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.