Evidence map›Paper›PMID 34740359›Full record

ReviewCardiovascular diabetology2021

Heart failure in type 2 diabetes: current perspectives on screening, diagnosis and management.

Antonio Ceriello, Doina Catrinoiu, Chanchal Chandramouli, Francesco Cosentino, Annique Cornelia Dombrowsky, Baruch Itzhak, Nebojsa Malić Lalic, Francesco Prattichizzo, Oliver Schnell, Petar M Seferović and 3 more

Registry-linked trialOpen access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Cardiovascular diabetology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06453967 (Impact of Blood Glucose Levels on in ICU Morbidity and Mortality in Patients With Acute Decompensated Heart Failure), which is not on this map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06453967 unknown statusnot on this mapstarted 2024, after this paper: background citation

Impact of Blood Glucose Levels on in ICU Morbidity and Mortality in Patients With Acute Decompensated Heart Failure

TypeobservationalSponsorAssiut UniversityRan2024 to 2025Enrolled96ConditionsHeart FailureArmsblood glucose levels
3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it, 99 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 8 countries.

Antonio CerielloIRCCS MultiMedica, Via Gaudenzio Fantoli, 16/15, 20138, Milan, Italy. antonio.ceriello@hotmail.it.ORCID 0000-0001-8122-3203
Doina CatrinoiuFaculty of Medicine, Clinical Center of Diabetes, Nutrition and Metabolic Diseases, Ovidius University of Constanta, Constanta, Romania.
Chanchal ChandramouliDuke-NUS Medical School, Singapore, Singapore.
Francesco CosentinoUnit of Cardiology, Karolinska Institute, Karolinska University Hospital Solna, Stockholm, Sweden.
Annique Cornelia DombrowskySciarc GmbH, Baierbrunn, Germany.
Baruch ItzhakClalit Health Services and Technion Faculty of Medicine, Haifa, Israel.
Nebojsa Malić LalicSchool of Medicine, Clinic for Endocrinology, Diabetes and Metabolic Diseases, University of Belgrade, Belgrade, Serbia.
Francesco PrattichizzoIRCCS MultiMedica, Via Gaudenzio Fantoli, 16/15, 20138, Milan, Italy.
Oliver SchnellForschergruppe Diabetes e. V. at Helmholtz Centre Munich GmbH, Munich, Germany.
Petar M SeferovićSchool of Medicine, University of Belgrade, Belgrade University Medical Center, Belgrade, Serbia.
Paul ValensiUnit of Endocrinology, Diabetology, Nutrition, Jean Verdier Hospital, AP-HP, CRNH-IdF, CINFO, Paris 13 University, Bondy, France.
Eberhard StandlForschergruppe Diabetes e. V. at Helmholtz Centre Munich GmbH, Munich, Germany.
D&CVD EASD Study Group
Helmholtz Zentrum München · DEMultiMedica · ITUniversity of Belgrade · RSClalit Health Services · ILDuke-NUS Medical School · SGKarolinska University Hospital · SEOvidius University · ROUniversité Sorbonne Paris Nord · FR

Funding

Roche Diagnostics International Ltd. Roche Diagnostics International Ltd.
6 · The paper itself

Abstract

Type 2 diabetes is one of the most relevant risk factors for heart failure, the prevalence of which is increasing worldwide. The aim of the review is to highlight the current perspectives of the pathophysiology of heart failure as it pertains to type 2 diabetes. This review summarizes the proposed mechanistic bases, explaining the myocardial damage induced by diabetes-related stressors and other risk factors, i.e., cardiomyopathy in type 2 diabetes. We highlight the complex pathology of individuals with type 2 diabetes, including the relationship with chronic kidney disease, metabolic alterations, and heart failure. We also discuss the current criteria used for heart failure diagnosis and the gold standard screening tools for individuals with type 2 diabetes. Currently approved pharmacological therapies with primary use in type 2 diabetes and heart failure, and the treatment-guiding role of NT-proBNP are also presented. Finally, the influence of the presence of type 2 diabetes as well as heart failure on COVID-19 severity is briefly discussed.

Indexed as

Disease ManagementBiomarkersCOVID-19Diabetes Mellitus, Type 2Glycated HemoglobinHeart FailureHumansMass ScreeningNatriuretic Peptide, BrainPeptide FragmentsPrognosisBiomarkersGlycated Hemoglobinhemoglobin A1c protein, humanNatriuretic Peptide, BrainPeptide Fragmentspro-brain natriuretic peptide (1-76)GuidelinesHeart failureNT-proBNPType 2 diabetes

Identifiers

PMID34740359
PMCPMC8571004
OpenAlexW3208377810

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.