Evidence map›Paper›PMID 34744611›Full record

ArticleFrontiers in neuroscience2021

Case Report: Serial MR Vessel Wall Imaging Visualizes the Response of Intracranial Plaques and Assists in Decision-Making.

Jiayu Xiao, Matthew M Padrick, Shlee S Song, Zhaoyang Fan, Konrad H Schlick

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Jiayu XiaoDepartments of Radiology, Keck School of Medicine of USC, Los Angeles, CA, United States.
Matthew M PadrickDepartment of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Shlee S SongDepartment of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Zhaoyang FanDepartments of Radiology, Keck School of Medicine of USC, Los Angeles, CA, United States.
Konrad H SchlickDepartment of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, United States.
Cedars-Sinai Medical Center · US

Funding

Longitudinal and quantitative MR plaque imaging for prediction of response to medical management in symptomatic intracranial atherosclerosisR01HL147355 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI FAN, ZHAOYANG · 2019 to 2023
$2.1M
NHLBI NIH HHS R01 HL147355
6 · The paper itself

Abstract

Intracranial atherosclerotic disease (ICAD) is a dynamic process that leads to ischemic stroke. Symptomatic ICAD patients still suffer a high recurrent rate even under standard treatment. In this case report, to better understand the response of intracranial atherosclerotic plaques to medication, serial MR imaging was added to standard clinical workup in a 47-year-old male patient with acute occipital lobe infarction at baseline, 3-month, 6-month, and 12-month post index stroke to directly visualize the morphology and signal change of plaques. We noticed that one of the plaques showed dramatic worsening at 3-month imaging follow-up despite a decrease in low-density lipoprotein level. Early identification of patients who do not respond well to medication is critical to prevent the recurrence of cardiovascular events in ICAD patients.

Indexed as

follow-up studyintracranial atherosclerosisplaquestrokevessel wall imaging

Identifiers

PMID34744611
PMCPMC8564011
OpenAlexW3205890779

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.