Evidence map›Paper›PMID 34748249›Full record

ReviewJournal of neuroendocrinology2021

Phasic spiking in vasopressin neurons: How and Why.

Duncan J MacGregor

Open access · hybridAbstract readReview
In one paragraph

Review in Journal of neuroendocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Mathematical modelling of the oxytocin and vasopressin secretory system.Current opinion in endocrine and metabolic research · 2022
    Review
  2. Phasic spiking in vasopressin neurons: How and Why.Journal of neuroendocrinology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Duncan J MacGregorCentre for Discovery Brain Sciences, University of Edinburgh, Edinburgh, UK.ORCID 0000-0002-3046-6640
University of Edinburgh · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The plain title might have been an almost retro sounding grumpy retort, but it has inspired a journey of sorts, and something along the way I hope you won't have come across before. An opinionated exploration of the distinctive phasic spiking patterns of magnocellular vasopressin neurons of the supraoptic and paraventricular nuclei of the hypothalamus. A mostly life essential population of neurons that signal the kidneys to regulate water loss in response to signals that encode plasma volume and osmotic pressure, as well as regulating blood pressure, and possibly metabolism and social behaviour. The viewpoint of a modeller shorn of any explicit maths.

Indexed as

Paraventricular Hypothalamic NucleusSupraoptic NucleusHypothalamusNeuronsOxytocinVasopressinsOxytocinVasopressinsmodellingpatterningphasic firingsecretionspikingvasopressin

Identifiers

PMID34748249
PMCPMC11475727
OpenAlexW3199001114

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.