Evidence map›Paper›PMID 34753754›Full record

ArticleBMJ open2021

Effect of body mass index on vertebral and hip fractures in older people and differences according to sex: a retrospective Japanese cohort study.

Kyohei Shiomoto, Akira Babazono, Yumi Harano, Takako Fujita, Peng Jiang, Sung-A Kim, Yasuharu Nakashima

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Association between obesity and the prevalence of fractures: a population-based cross-sectional study in China.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025
    Article
  3. Review
  4. Observational
  5. Article
  6. Prognostic Factors of Hip Fracture in Elderly: A Systematic Review.International journal of preventive medicine · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Kyohei ShiomotoArtificial Joints and Biomaterials, Faculty of Medical Science, Kyushu University, Fukuoka, Japan k-shio@ortho.med.kyushu-u.ac.jp.ORCID 0000-0003-1741-6929
Akira BabazonoHealth Care Administration and Management, Kyushu University Faculty of Medicine Graduate School of Medical Science, Fukuoka, Japan.
Yumi HaranoHealth Care Administration and Management, Kyushu University Faculty of Medicine Graduate School of Medical Science, Fukuoka, Japan.
Takako FujitaHealth Care Administration and Management, Kyushu University Faculty of Medicine Graduate School of Medical Science, Fukuoka, Japan.ORCID 0000-0002-6890-6533
Peng JiangHealth Care Administration and Management, Kyushu University Faculty of Medicine Graduate School of Medical Science, Fukuoka, Japan.
Sung-A KimHealth Care Administration and Management, Kyushu University Faculty of Medicine Graduate School of Medical Science, Fukuoka, Japan.ORCID 0000-0002-3367-5763
Yasuharu NakashimaOrthopaedic Surgery, Kyushu University Faculty of Medicine Graduate School of Medical Science, Fukuoka, Japan.
Kyushu University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe purpose of this study was to investigate the incidence of vertebral and hip fractures in the older people and to clarify the relationship between these fractures and body mass index (BMI) along with the impact of sex differences.

participantsOlder people aged ≥75 years who underwent health examinations in 2010 and were living in the Fukuoka Prefecture, Japan were included in the study. A total of 24 691 participants were included; the mean age was 79.4±4.3 years, 10 853 males and 13 838 females, and an the mean duration of observation was 6.9±1.6 years. PRIMARY AND SECONDARY OUTCOME MEASURES: We estimated the incidence of vertebral and hip fractures by BMI category (underweight: <18.5 kg/m

resultsThe incidence of vertebral and hip fractures was 16.8% and 6.5%, respectively. The cumulative incidence of vertebral and hip fracture at the last observation (8 years) in each BMI groups (underweight/normal weight/overweight and obese) estimated using the Kaplan-Meier curve was 14.7%/10.4%/9.0% in males and 24.9%/23.0%/21.9% in females, and 6.3%/2.9%/2.4% in males and 14.1%/9.0%/8.1% in females, respectively, and both fractures were significantly higher in underweight groups regardless of sex. Multivariable Cox proportional hazards models showed that underweight was a significant risk factor only in males for vertebral fractures and in both males and females for hip fractures.

conclusionUnderweight was associated with fractures in the ageing population, but there was a sex difference in the effect for vertebral fractures.

Indexed as

Hip FracturesAgedAged, 80 and overBody Mass IndexCohort StudiesFemaleHumansIncidenceJapanMaleRetrospective StudiesRisk Factorsadult orthopaedicsepidemiologypublic health

Identifiers

PMID34753754
PMCPMC8578981
OpenAlexW3213312006

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.