Evidence map›Paper›PMID 34754153›Full record

ReviewWorld journal of gastroenterology2021

Current and emerging therapeutic strategies in pancreatic cancer: Challenges and opportunities.

Manish Manrai, T V S V G K Tilak, Saurabh Dawra, Sharad Srivastava, Anupam Singh

Abstract readReview
In one paragraph

Review in World journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Comparison of standardWorld journal of methodology · 2025
    Article
  2. Science advances · 2025
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  6. Review
  7. Article
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  12. Research Progress on TRPA1 in Diseases.The Journal of membrane biology · 2023
    Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Manish ManraiDepartment of Internal Medicine, Armed Forces Medical College, Pune 411040, Maharashtra, India. manishmanrai@yahoo.com.
T V S V G K TilakDepartment of Internal Medicine, Armed Forces Medical College, Pune 411040, Maharashtra, India.
Saurabh DawraDepartment of Internal Medicine, Command Hospital, Pune 411040, Maharashtra, India.
Sharad SrivastavaDepartment of Internal Medicine, Command Hospital, Pune 411040, Maharashtra, India.
Anupam SinghDepartment of Gastroenterology, Post Graduate Institute of Medical Education and Research, Chandigarh 160011, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic carcinoma (PC) is one of the leading causes of cancer-related deaths worldwide. Despite early detection and advances in therapeutics, the prognosis remains dismal. The outcome and therapeutic approach are dependent on the stage of PC at the time of diagnosis. The standard of care is surgery, followed by adjuvant chemotherapy. The advent of newer drugs has changed the landscape of adjuvant therapy. Moreover, recent trials have highlighted the role of neoadjuvant therapy and chemoradiotherapy for resectable and borderline resectable PC. As we progress towards a better understanding of tumor biology, genetics, and microenvironment, novel therapeutic strategies and targeted agents are now on the horizon. We have described the current and emerging therapeutic strategies in PC.

Indexed as

Carcinoma, Pancreatic DuctalPancreatic NeoplasmsChemoradiotherapyChemotherapy, AdjuvantHumansNeoadjuvant TherapyPancreatectomyTumor MicroenvironmentAdjuvant therapyBorderline resectable pancreatic carcinomaLocally advanced pancreatic carcinomaNeoadjuvant therapyNewer advances in pancreatic carcinomaResectable pancreatic carcinoma

Identifiers

PMID34754153
PMCPMC8554408

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.