Evidence map›Paper›PMID 34755232›Full record

ReviewInflammopharmacology2021

Osteoarthritis complications and the recent therapeutic approaches.

Manal A Abdel-Aziz, Helmy M S Ahmed, Aziza A El-Nekeety, Mosaad A Abdel-Wahhab

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in Inflammopharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07618403 (Evaluating The Predictive Effect of Treatment Expectations on Response to A Physical Therapy Program in Patients With Knee Osteoarthritis), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07618403 recruitingnot on this mapstarted 2026, after this paper: background citation

Evaluating The Predictive Effect of Treatment Expectations on Response to A Physical Therapy Program in Patients With Knee Osteoarthritis

TypeobservationalSponsorGazi UniversityRan2026 to 2027Enrolled84ConditionsGonarthrosis, Primary, Physical Therapy, Patients' ExpectationsArmsPhysical Therapy
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 32 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Manal A Abdel-AzizToxicology and Pharmacology Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Helmy M S AhmedToxicology and Pharmacology Department, Faculty of Pharmacy, Cairo University, Cairo, Egypt. helmy-moawad@yahoo.com.
Aziza A El-NekeetyFood Toxicology and Contaminants Department, National Research Center, Dokki, Cairo, Egypt.
Mosaad A Abdel-WahhabFood Toxicology and Contaminants Department, National Research Center, Dokki, Cairo, Egypt. mosaad_abdelwahhab@yahoo.com.ORCID http://orcid.org/0000-0002-7174-3341
Cairo University · EGNational Research Centre · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The accelerated prevalence of osteoarthritis (OA) disease worldwide and the lack of convenient management led to the frequent search for unprecedented and specific treatment approaches. OA patients usually suffer from many annoying complications that negatively influence their quality of life, especially in the elderly. Articular erosions may lead eventually to the loss of joint function as a whole which occurs over time according to the risk factors presented in each case and the grade of the disease. Conventional therapies are advancing, showing most appropriate results but still greatly associated with many adverse effects and have restricted curative actions as well. Hence, novel management tools are usually required. In this review, we summarized the recent approaches in OA treatment and the role of natural products, dietary supplements and nanogold application in OA treatment to provide new research tracks for more therapeutic opportunities to those who are in care in this field.

Indexed as

Quality of LifeAgedAnimalsBiological ProductsDietary SupplementsGoldHumansMetal NanoparticlesOsteoarthritisRisk FactorsBiological ProductsGoldDietary supplementsInflammationNanoparticlesNatural productsOsteoarthritis

Identifiers

PMID34755232
OpenAlexW3213197915

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.