Evidence map›Paper›PMID 34764718›Full record

ArticleJournal of ginseng research2021

Whitening and inhibiting NF-κB-mediated inflammation properties of the biotransformed green ginseng berry of new cultivar K1, ginsenoside Rg2 enriched, on B16 and LPS-stimulated RAW 264.7 cells.

Xing Yue Xu, Eun Seob Yi, Chang Ho Kang, Ying Liu, Yeong-Geun Lee, Han Sol Choi, Hyun Bin Jang, Yue Huo, Nam-In Baek, Deok Chun Yang and 1 more

Open access · goldAbstract read
In one paragraph

Article in Journal of ginseng research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Combination ofFrontiers in pharmacology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Xing Yue XuGraduate School of Biotechnology, and College of Life Science, Kyung Hee University, Yongin-si, Gyeonggi-do, Republic of Korea.
Eun Seob YiGraduate School of Biotechnology, and College of Life Science, Kyung Hee University, Yongin-si, Gyeonggi-do, Republic of Korea.
Chang Ho KangDivision of Applied Life Science and PMBBRC, Gyeongsang National University, Jinju, Republic of Korea.
Ying LiuGraduate School of Biotechnology, and College of Life Science, Kyung Hee University, Yongin-si, Gyeonggi-do, Republic of Korea.
Yeong-Geun LeeGraduate School of Biotechnology, and College of Life Science, Kyung Hee University, Yongin-si, Gyeonggi-do, Republic of Korea.
Han Sol ChoiGraduate School of Biotechnology, and College of Life Science, Kyung Hee University, Yongin-si, Gyeonggi-do, Republic of Korea.
Hyun Bin JangGraduate School of Biotechnology, and College of Life Science, Kyung Hee University, Yongin-si, Gyeonggi-do, Republic of Korea.
Yue HuoGraduate School of Biotechnology, and College of Life Science, Kyung Hee University, Yongin-si, Gyeonggi-do, Republic of Korea.
Nam-In BaekGraduate School of Biotechnology, and College of Life Science, Kyung Hee University, Yongin-si, Gyeonggi-do, Republic of Korea.
Deok Chun YangGraduate School of Biotechnology, and College of Life Science, Kyung Hee University, Yongin-si, Gyeonggi-do, Republic of Korea.
Yeon-Ju KimGraduate School of Biotechnology, and College of Life Science, Kyung Hee University, Yongin-si, Gyeonggi-do, Republic of Korea.
Kyung Hee University · KRGyeongsang National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMain bioactive constituents and pharmacological functions of ripened red ginseng berry (

methodsGinsenosides of new green berry cultivar K-1 (GK-1) were identified by HPLC-QTOF/MS. Ginsenosides bioconversion in GK-1 by bgp1 enzyme was confirmed with HPLC and TLC. Then, mechanisms of GK-1 and β-glucosidase (bgp1) biotransformed GK-1 (BGK-1) were determined by Quantitative Reverse Transcription-Polymerase Chain Reaction and Western blot.

resultsGK-1 possesses highest ginsenosides especially ginsenoside-Re amongst seven ginseng cultivars including (Chunpoong, Huangsuk, Kumpoong, K-1, Honkaejong, Gopoong, and Yunpoong). Ginseng root's biomass is not affected with the harvest of GK-1 at 3 weeks after flowering period. Then, Re is bio-converted into a promising pharmaceutical effect of Rg2

conclusionThese results reported effective whitening and anti-inflammatory of BGK-1 as compared to GK-1.

Indexed as

Anti-inflammationGinseng cultivar K-1GinsenosidesWhiteningβ-glucosidase (bgp1)

Identifiers

PMID34764718
PMCPMC8569260
OpenAlexW3138960291

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.