Evidence mapPaperPMID 34764875Full record

ReviewFrontiers in pharmacology2021

Glucosinolates From Cruciferous Vegetables and Their Potential Role in Chronic Disease: Investigating the Preclinical and Clinical Evidence.

Emma L Connolly, Marc Sim, Nikolaj Travica, Wolfgang Marx, Gemma Beasy, Gordon S Lynch, Catherine P Bondonno, Joshua R Lewis, Jonathan M Hodgson, Lauren C Blekkenhorst

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Organosulfur Compounds: Potential Therapeutics for Parkinson's Disease.CNS & neurological disorders drug targets · 2026
    Review
  12. Review
  13. Biochemical characterization of twoFrontiers in plant science · 2026
    Article
  14. Article
  15. Glucosinolate-Derived Metabolites fromMolecules (Basel, Switzerland) · 2025
    Article
  16. Article
  17. mLife · 2025
    Article
  18. Nutrients · 2025
    Article
  19. Review
  20. Review

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Emma L ConnollyInstitute for Nutrition Research, School of Medical and Health Sciences, Edith Cowan University, Perth, WA, Australia.
Marc SimInstitute for Nutrition Research, School of Medical and Health Sciences, Edith Cowan University, Perth, WA, Australia.
Nikolaj TravicaIMPACT-The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong, VIC, Australia.
Wolfgang MarxIMPACT-The Institute for Mental and Physical Health and Clinical Translation, School of Medicine, Barwon Health, Deakin University, Geelong, VIC, Australia.
Gemma BeasyQuadram Institute Bioscience, Norwich, United Kingdom.
Gordon S LynchDepartment of Anatomy and Physiology, Centre for Muscle Research, School of Biomedical Sciences, The University of Melbourne, Melbourne, VIC, Australia.
Catherine P BondonnoInstitute for Nutrition Research, School of Medical and Health Sciences, Edith Cowan University, Perth, WA, Australia.
Joshua R LewisInstitute for Nutrition Research, School of Medical and Health Sciences, Edith Cowan University, Perth, WA, Australia.
Jonathan M HodgsonInstitute for Nutrition Research, School of Medical and Health Sciences, Edith Cowan University, Perth, WA, Australia.
Lauren C BlekkenhorstInstitute for Nutrition Research, School of Medical and Health Sciences, Edith Cowan University, Perth, WA, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An increasing body of evidence highlights the strong potential for a diet rich in fruit and vegetables to delay, and often prevent, the onset of chronic diseases, including cardiometabolic, neurological, and musculoskeletal conditions, and certain cancers. A possible protective component, glucosinolates, which are phytochemicals found almost exclusively in cruciferous vegetables, have been identified from preclinical and clinical studies. Current research suggests that glucosinolates (and isothiocyanates) act

Indexed as

cancercardiometabolic disorderscruciferous vegetablesglucosinolatesisothiocyanatesmusculoskeletal healthneurological disorders

Identifiers

PMID34764875
PMCPMC8575925

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.