ReviewReproductive biomedicine & society online2022
Metabolic risk factors and fertility disorders: A narrative review of the female perspective.
Review in Reproductive biomedicine & society online, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Determining risk factors predicting miscarriage among couples undergoing assisted reproductive treatment: a systematic review.BMC pregnancy and childbirth · 2026Pooled it
- Association between history of fertility problems and pregnancy and birth complications: A longitudinal population-based cohort study.Acta obstetricia et gynecologica Scandinavica · 2026Article
- Body mass index as a key determinant of oxidative stress in women undergoing infertility treatment.Frontiers in reproductive health · 2026Article
- Elevated plasma glucose links intrafollicular bile acids to altered embryological outcomes in IVF patients.Journal of ovarian research · 2025Article
- Novel link between plasma bilirubin and anti-inflammatory miRNA profiles in follicular fluid of IVF patients.American journal of physiology. Endocrinology and metabolism · 2025Article
- The Relationship Between Obesity, Bariatric Surgery, and Infertility: A Systematic Review.Life (Basel, Switzerland) · 2025Review
- Reproductive History and Infertility Risk: Insights from the 2017-2020 National Health and Nutrition Examination Survey.International journal of women's health · 2025Article
- Impact of high-fructose diet and metformin on histomorphological and molecular parameters of reproductive organs and vaginal microbiota of female rat.Scientific reports · 2024Article
- Hypogonadism and nonalcoholic fatty liver disease.Endocrine · 2024Review
- The discriminatory capability of anthropometric measures in predicting reproductive outcomes in Chinese women with PCOS.Journal of ovarian research · 2024Article
- Article
- Investigating the metabolomic pathways in female reproductive endocrine disorders: a Mendelian randomization study.Frontiers in endocrinology · 2024Article
- The interplay of maternal and offspring obesogenic diets: the impact on offspring metabolism and muscle mitochondria in an outbred mouse model.Frontiers in physiology · 2024Article
- Amino Acid Profiling of Follicular Fluid in Assisted Reproduction Reveals Important Roles of Several Amino Acids in Patients with Insulin Resistance.International journal of molecular sciences · 2023Article
- PFOS-elicited metabolic perturbation in liver and fatty acid metabolites in testis of adult mice.Frontiers in endocrinology · 2023Article
- Vitamin B12 Status and Gut Microbiota among Saudi Females with Obesity.Foods (Basel, Switzerland) · 2022Article
- Obesity alters the mouse endometrial transcriptome in a cell context-dependent manner.Reproductive biology and endocrinology : RB&E · 2022Article
- Families formed through assisted reproductive technology: Causes, experiences, and consequences in an international context.Reproductive biomedicine & society online · 2022Article
- Assessment of Left Ventricular Function in Patients with Metabolic Syndrome: A Strain Imaging Study.Journal of cardiovascular echographyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metabolic risk factors such as obesity are considered major obstacles to female fertility. Chronic infertility imposes psychological and social burdens on women because infertility violates societal gender roles. Although the prevalence of obesity among women is expected to increase in the future, the relevance of metabolic status for fertility is still underestimated. However, the assessment of metabolic risk factors is highly relevant for understanding fertility disorders and improving infertility treatment. This narrative review discusses the associations of metabolic risk factors (e.g. obesity, female athlete triad, oxidative stress) with significant infertility. An electronic search was conducted for studies published between 2006 and 2020 in Cumulative Index to Nursing and Allied Health Literature, ScienceDirect, PubMed, Scopus, Google Scholar and related databases. In total, this search identified 19,309 results for polycystic ovary syndrome, 28,969 results for endometriosis, and only 1611 results for idiopathic and/or unknown infertility. For the present narrative review, 50 relevant studies were included: 19 studies were on obesity, 24 studies investigated the female athlete triad, and seven studies addressed other risk factors, including reactive oxygen species. This narrative review confirms the direct impact of obesity on female infertility, while the effect of other risk factors needs to be confirmed by large-scale population studies.
Indexed as
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.