Evidence map›Paper›PMID 34766865›Full record

ArticleRNA biology2021

Reproducible and efficient new method of RNA 3'-end labelling by CutA nucleotidyltransferase-mediated CC-tailing.

Rafal Tomecki, Kamil Kobylecki, Karolina Drazkowska, Malwina Hyjek-Skladanowska, Andrzej Dziembowski

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RNA biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Rafal TomeckiLaboratory of Rna Biology, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.ORCID 0000-0003-2473-5004
Kamil KobyleckiLaboratory of Rna Biology, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland.ORCID 0000-0003-3019-0274
Karolina DrazkowskaCentre of New Technologies, University of Warsaw, Warsaw, Poland.ORCID 0000-0003-2673-7126
Malwina Hyjek-SkladanowskaLaboratory of Protein Structure, International Institute of Molecular and Cell Biology, Warsaw, Poland.ORCID 0000-0001-8276-4845
Andrzej DziembowskiFaculty of Biology, Institute of Genetics and Biotechnology, University of Warsaw, Warsaw, Poland.ORCID 0000-0001-8492-7572
Institute of Biochemistry and Biophysics, Polish Academy of Sciences · PLInternational Institute of Molecular and Cell Biology · PLUniversity of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the development of non-radioactive DNA/RNA labelling methods, radiolabelled nucleic acids are commonly used in studies focused on the determination of RNA fate. Nucleic acid fragments with radioactive nucleotide analoguesincorporated into the body or at the 5' or 3' terminus of the molecule can serve as probes in hybridization-based analyses of

Indexed as

Cytidine TriphosphateIn Vitro TechniquesIsotope LabelingNucleotidesNucleotidyltransferasesPhosphorus RadioisotopesRNARNA Ligase (ATP)Staining and LabelingSubstrate SpecificityUridine TriphosphateCytidine TriphosphateNucleotidesNucleotidyltransferasesPhosphorus-32Phosphorus RadioisotopesRNARNA Ligase (ATP)Uridine Triphosphate3ʹ-end RNA labellingCutADis3dsRNAexoribonuclease directionalitynucleotidyltransferaseradioactive nucleotidesssRNAT4 RNA ligase IXrn1

Identifiers

PMID34766865
PMCPMC8791449
OpenAlexW3212145586

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.