Evidence map›Paper›PMID 34767486›Full record

ArticleAmerican journal of physiology. Heart and circulatory physiology2022

Protein tyrosine phosphatase receptor-ζ1 deletion triggers defective heart morphogenesis in mice and zebrafish.

Stamatiki Katraki-Pavlou, Pinelopi Kastana, Dimitris Bousis, Despoina Ntenekou, Aimilia Varela, Constantinos H Davos, Sophia Nikou, Eleni Papadaki, Grigorios Tsigkas, Emmanouil Athanasiadis and 4 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in American journal of physiology. Heart and circulatory physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Midkine-A novel player in cardiovascular diseases.Frontiers in cardiovascular medicine · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Stamatiki Katraki-PavlouLaboratory of Molecular Pharmacology, Department of Pharmacy, School of Health Sciences, University of Patras, Patras, Greece.
Pinelopi KastanaLaboratory of Molecular Pharmacology, Department of Pharmacy, School of Health Sciences, University of Patras, Patras, Greece.
Dimitris BousisLaboratory of Molecular Pharmacology, Department of Pharmacy, School of Health Sciences, University of Patras, Patras, Greece.
Despoina NtenekouLaboratory of Molecular Pharmacology, Department of Pharmacy, School of Health Sciences, University of Patras, Patras, Greece.
Aimilia VarelaCardiovascular Research Laboratory, Biomedical Research Foundation, Academy of Athens, Athens, Greece.
Constantinos H DavosCardiovascular Research Laboratory, Biomedical Research Foundation, Academy of Athens, Athens, Greece.
Sophia NikouDepartment of Anatomy-Histology-Embryology, Medical School, University of Patras, Patras, Greece.
Eleni PapadakiDepartment of Anatomy-Histology-Embryology, Medical School, University of Patras, Patras, Greece.
Grigorios TsigkasDepartment of Cardiology, Patras University Hospital, Rio, Greece.ORCID 0000-0002-2779-0765
Emmanouil AthanasiadisSystems Biology Center, Biomedical Research Foundation, Academy of Athens, Athens, Greece.ORCID 0000-0002-2771-5562
Gonzalo HerradonDepartment of Pharmaceutical and Health Sciences, Facultad de Farmacia, Universidad San Pablo-CEU, CEU Universities, Madrid, Spain.
Constantinos M MikelisLaboratory of Molecular Pharmacology, Department of Pharmacy, School of Health Sciences, University of Patras, Patras, Greece.
Dimitris BeisZebrafish Disease Models Laboratory, Center for Clinical, Experimental Surgery and Translational Research, Biomedical Research Foundation Academy of Athens, Athens, Greece.ORCID 0000-0003-2579-7848
Evangelia PapadimitriouLaboratory of Molecular Pharmacology, Department of Pharmacy, School of Health Sciences, University of Patras, Patras, Greece.ORCID 0000-0001-6429-4325
University of Patras · GRAcademy of Athens · GRTexas Tech University · USUniversidad San Pablo CEU · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Protein tyrosine phosphatase receptor-

Indexed as

OrganogenesisAnimalsGene DeletionHeartMiceMyocardiumReceptor-Like Protein Tyrosine Phosphatases, Class 5ZebrafishZebrafish ProteinsPtprz1 protein, mouseptprz1 protein, zebrafishReceptor-Like Protein Tyrosine Phosphatases, Class 5Zebrafish Proteinsangiogenesiscardiac morphogenesiscardiogenesistyrosine phosphatasezebrafish

Identifiers

PMID34767486
PMCPMC8754060
OpenAlexW3212633383

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.