Evidence map›Paper›PMID 34768053›Full record

ArticleDrug and alcohol dependence2021

Estimating the impact on initiating medications for opioid use disorder of state policies expanding Medicaid and prohibiting substance use during pregnancy.

Sugy Choi, Michael D Stein, Julia Raifman, David Rosenbloom, Jack A Clark

Open access · greenAbstract read
In one paragraph

Article in Drug and alcohol dependence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sugy ChoiDepartment of Health Law, Policy & Management, Boston University School of Public Health, Boston, MA 02118, USA; Department of Population Health, New York University Grossman School of Medicine, New York, NY 10016, USA. Electronic address: sugy.choi@nyulangone.org.
Michael D SteinDepartment of Health Law, Policy & Management, Boston University School of Public Health, Boston, MA 02118, USA.
Julia RaifmanDepartment of Health Law, Policy & Management, Boston University School of Public Health, Boston, MA 02118, USA.
David RosenbloomDepartment of Health Law, Policy & Management, Boston University School of Public Health, Boston, MA 02118, USA.
Jack A ClarkDepartment of Health Law, Policy & Management, Boston University School of Public Health, Boston, MA 02118, USA.
Boston University · USNew York University · US

Funding

Integrated Care for Addiction, HIV and HCV Research and Education (ICAHRE)T32DA041898 · NIDA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Rachel Sayko Adams, Michael D Stein · 2017 to 2026
$3.8M
The Brown Initiative in HIV and AIDS Clinical Research for Minority CommunitiesR25MH083620 · NIMH · MIRIAM HOSPITAL · PI NUNN, AMY STEWART · 2008 to 2025
$3.7M
The Lifespan/Brown Criminal Justice Research Program on Substance Use and HIVR25DA037190 · NIDA · MIRIAM HOSPITAL · PI CURT G BECKWITH · 2014 to 2026
$3.5M
NIDA NIH HHS R25 DA037190NIDA NIH HHS T32 DA041898NIMH NIH HHS R25 MH083620
6 · The paper itself

Abstract

backgroundMedicaid expansion increased access to addiction treatment services for pregnant women. However, states' imposition of civil or criminal child abuse sanctions for drug use during pregnancy could inhibit access to treatment. We estimated the effects of Medicaid expansion on pregnant women's medications for opioid use disorder (MOUD) use, and its interaction with statutes that prohibit substance use during pregnancy.

methodsUsing the Treatment Episode Dataset for Discharge (2010-2018), we identified the initial treatment episode of pregnant women with opioid use disorder (OUD). We described changes in MOUD use and estimated adjusted difference-in-differences and event study models to evaluate differences in changes in MOUD between states that prohibit substance use during pregnancy and states that do not.

findingsAmong a total of 16,070 treatment episodes for pregnant women with OUD from 2010 to 2018, most (74%) were in states that expanded Medicaid. By one year post-expansion, the proportion of episodes receiving MOUD in states not prohibit substance use during pregnancy increased by 8.7% points (95% CI: 2.7, 14.7) from the pre-expansion period compared to a 5.6% point increase in states prohibiting substance use during pregnancy (95% CI: -3.3, 14.8). In adjusted event study analysis, the expansion was associated with an increase in MOUD use by 15.3% by year 2 in states not prohibiting versus 1.5% percentage points in states prohibiting substance use during pregnancy, respectively.

conclusionsState policies prohibiting substance use during pregnancy may limit the salutary effects of Medicaid expansion for pregnant women who could benefit from MOUD treatment.

Indexed as

BuprenorphineOpioid-Related DisordersPharmaceutical PreparationsAnalgesics, OpioidChildFemaleHumansMedicaidOpiate Substitution TreatmentPolicyPregnancyUnited StatesAnalgesics, OpioidBuprenorphinePharmaceutical PreparationsHealth policyMedication-assisted treatmentPregnancyPunitiveWomen’s rights

Identifiers

PMID34768053
PMCPMC8671210
OpenAlexW3211170499

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.