Evidence mapPaperPMID 34768560Full record

ArticleJournal of clinical medicine2021

Aging in Down Syndrome: Latest Clinical Advances and Prospects.

Alessandra C Martini, Melissa J Alldred, Ann-Charlotte Granholm

Abstract readEditorial
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Down Syndrome Biobank Consortium: A perspective.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alessandra C MartiniDepartment of Pathology and Lab. Medicine, University of California Irvine, Irvine, CA 92697, USA.
Melissa J AlldredNathan Kline Institute, NYU Grossman Medical School, 140 Old Orangeburg Rd., Orangeburg, NY 10962, USA.
Ann-Charlotte GranholmKnoebel Institute for Healthy Aging, University of Denver, Denver, CO 80208, USA.

Funding

TRANSGENIC COREP01AG017617 · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · 2000 to 2005
$8.9M
TAU, AB, SYNUCLEIN AND NITRATIVE/OXIDATIVE DAMAGE IN MCIP01AG014449 · UNIVERSITY OF PITTSBURGH · 1997 to 2005
$7.8M
NIA NIH HHS P01 AG014449NIH HHS P01AG014449NIH HHS P01AG017617NIH HHS R01AG061566)NIH HHS R01AG070153NIH HHS R21AG070297
6 · The paper itself

Abstract

Down syndrome (DS), or trisomy 21, is the most common genetic cause of intellectual disability [...].

Identifiers

PMID34768560
PMCPMC8584622

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.