Evidence map›Paper›PMID 34769014›Full record

ArticleInternational journal of molecular sciences2021

Isoform-Specific Effects of Apolipoprotein E on Hydrogen Peroxide-Induced Apoptosis in Human Induced Pluripotent Stem Cell (iPSC)-Derived Cortical Neurons.

Huiling Gao, Wei Zheng, Cheng Li, He Xu

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Neuroprotection: Rescue from Neuronal Death in the Brain 2.0.International journal of molecular sciences · 2023
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Huiling GaoCollege of Life and Health Sciences, Northeastern University, Shenyang 110819, China.
Wei ZhengDepartment of Histology and Embryology, China Medical University, Shenyang 110122, China.
Cheng LiDepartment of Immunology, China Medical University, Shenyang 110122, China.
He XuDepartment of Histology and Embryology, Faculty of Medicine, Shenzhen University, Shenzhen 518061, China.ORCID 0000-0002-9087-9041
China Medical University · CNNortheastern University · CNShenzhen University · CN

Funding

National Natural Science Foundation of China 81471112National Natural Science Foundation of China 81601113National Natural Science Foundation of China 81771174Research Start-up Funds for Young Investigators in Shenzhen University 860-000002111208
6 · The paper itself

Abstract

Hydrogen peroxide (H

Indexed as

Apolipoproteins EApoptosisBrainCell LineHEK293 CellsHumansHydrogen PeroxideInduced Pluripotent Stem CellsNeuronsProtein IsoformsSignal TransductionApoE protein, humanApolipoproteins EHydrogen PeroxideProtein IsoformsAlzheimer’s diseaseapolipoprotein EapoptosisiPSC-derived cortical neuronsneurodegeneration

Identifiers

PMID34769014
PMCPMC8584079
OpenAlexW3208521027

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.