Evidence map›Paper›PMID 34769138›Full record

ReviewInternational journal of molecular sciences2021

Trace Element Selenium Effectively Alleviates Intestinal Diseases.

Ruihua Ye, Jiaqiang Huang, Zixu Wang, Yaoxing Chen, Yulan Dong

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Selenium: A Key Element in Inflammatory Bowel Disease.Antioxidants (Basel, Switzerland) · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Absorption, Distribution, Metabolism, and Excretion of [Molecules (Basel, Switzerland) · 2023
    Article
  18. Article
  19. Consequences of Disturbing Manganese Homeostasis.International journal of molecular sciences · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ruihua YeCollege of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Jiaqiang HuangKey Laboratory of Precision Nutrition and Food Quality, Ministry of Education, China Agricultural University, Beijing 100193, China.
Zixu WangCollege of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Yaoxing ChenCollege of Veterinary Medicine, China Agricultural University, Beijing 100193, China.ORCID 0000-0003-2576-5977
Yulan DongCollege of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
China Agricultural University · CN

Funding

National Natural Science Foundation of Beijing 6172022National Natural Science Foundation of China 31272483National Natural Science Foundation of China 31572476National Natural Science Foundation of China 31972087National Natural Science Foundation of China 31972633
6 · The paper itself

Abstract

Selenium (Se) is an essential trace element in the body. It is mainly used in the body in the form of selenoproteins and has a variety of biological functions. Intestinal diseases caused by chronic inflammation are among the most important threats to human health, and there is no complete cure at present. Due to its excellent antioxidant function, Se has been proven to be effective in alleviating intestinal diseases such as inflammatory bowel diseases (IBDs). Therefore, this paper introduces the role of Se and selenoproteins in the intestinal tract and the mechanism of their involvement in the mediation of intestinal diseases. In addition, it introduces the advantages and disadvantages of nano-Se as a new Se preparation and traditional Se supplement in the prevention and treatment of intestinal diseases, so as to provide a reference for the further exploration of the interaction between selenium and intestinal health.

Indexed as

AnimalsHumansIntestinal DiseasesNanoparticle Drug Delivery SystemSeleniumSelenoproteinsTrace ElementsNanoparticle Drug Delivery SystemSeleniumSelenoproteinsTrace ElementsIBDintestinal diseasesseleniumselenoproteinsSeNPs

Identifiers

PMID34769138
PMCPMC8584275
OpenAlexW3209872649

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.