Evidence map›Paper›PMID 34769201›Full record

ArticleInternational journal of molecular sciences2021

Regulation of p27 and Cdk2 Expression in Different Adipose Tissue Depots in Aging and Obesity.

Ignacio Colón-Mesa, Marta Fernández-Galilea, Neira Sáinz, Marta Lopez-Yus, Jose M Artigas, José Miguel Arbonés-Mainar, Elisa Félix-Soriano, Xavier Escoté, María Jesús Moreno-Aliaga

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Journal of traditional and complementary medicine · 2023
    Article
  7. International journal of molecular sciences · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Ignacio Colón-MesaCenter for Nutrition Research and Department of Nutrition, Food Science and Physiology, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0003-2963-9337
Marta Fernández-GalileaCenter for Nutrition Research and Department of Nutrition, Food Science and Physiology, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-4822-3188
Neira SáinzCenter for Nutrition Research and Department of Nutrition, Food Science and Physiology, University of Navarra, 31008 Pamplona, Spain.
Marta Lopez-YusAdipocyte and Fat Biology Laboratory (AdipoFat), Unidad de Investigación Traslacional, Instituto Aragonés de Ciencias de la Salud (IACS), Instituto de Investigación Sanitaria (IIS) Aragón, Hospital Universitario Miguel Servet, 50009 Zaragoza, Spain.
Jose M ArtigasRadiology Department, Hospital Universitario Miguel Servet, 50009 Zaragoza, Spain.
José Miguel Arbonés-MainarAdipocyte and Fat Biology Laboratory (AdipoFat), Unidad de Investigación Traslacional, Instituto Aragonés de Ciencias de la Salud (IACS), Instituto de Investigación Sanitaria (IIS) Aragón, Hospital Universitario Miguel Servet, 50009 Zaragoza, Spain.ORCID 0000-0002-8982-3737
Elisa Félix-SorianoCenter for Nutrition Research and Department of Nutrition, Food Science and Physiology, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0003-4633-1289
Xavier EscotéCenter for Nutrition Research and Department of Nutrition, Food Science and Physiology, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0003-1172-3995
María Jesús Moreno-AliagaCenter for Nutrition Research and Department of Nutrition, Food Science and Physiology, University of Navarra, 31008 Pamplona, Spain.ORCID 0000-0002-2018-6434
Universidad de Navarra · ESHospital Universitario Miguel Servet · ESInstituto de Salud Carlos III · ESNavarre Institute of Health Research · ESTechnological Center of Nutrition and Health · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aging usually comes associated with increased visceral fat accumulation, reaching even an obesity state, and favoring its associated comorbidities. One of the processes involved in aging is cellular senescence, which is highly dependent on the activity of the regulators of the cell cycle. The aim of this study was to analyze the changes in the expression of

Indexed as

Adipose Tissue, WhiteAgingAnimalsCyclin-Dependent Kinase 2Cyclin-Dependent Kinase Inhibitor p27FemaleMiceObesityCdk2 protein, mouseCdkn1b protein, mouseCyclin-Dependent Kinase 2Cyclin-Dependent Kinase Inhibitor p27adipose tissueagingCDK2cell cyclecyclinsobesityp27

Identifiers

PMID34769201
PMCPMC8584112
OpenAlexW3208069884

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.