Evidence map›Paper›PMID 34770502›Full record

ArticleSensors (Basel, Switzerland)2021

Can the AHCL System Be Used in T1D Patients with Borderline TDDI? A Case Report.

Anna Tekielak, Sebastian Seget, Ewa Rusak, Przemysława Jarosz-Chobot

Abstract readCase Reports
In one paragraph

Article in Sensors (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Safety, Metabolic and Psychological Outcomes of Medtronic MiniMed 780G™ in Children, Adolescents and Young Adults: A Systematic Review.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024
    Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Anna TekielakStudents' Scientific Association at the Department of Children's Diabetology, Medical University of Silesia, Medyków 16, 40-752 Katowice, Poland.
Sebastian SegetDepartment of Children's Diabetology, Medical University of Silesia, Medyków 16, 40-752 Katowice, Poland.
Ewa RusakDepartment of Children's Diabetology, Medical University of Silesia, Medyków 16, 40-752 Katowice, Poland.ORCID 0000-0002-4422-7704
Przemysława Jarosz-ChobotDepartment of Children's Diabetology, Medical University of Silesia, Medyków 16, 40-752 Katowice, Poland.ORCID 0000-0002-1120-0994

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Intensive insulin therapy using continuous subcutaneous insulin infusion (CSII) with continuous real-time glucose monitoring (rt CGM) is the best option for patients with T1D. The recent introduction of a technology called Advanced Hybrid Closed Loop (AHCL) represents a new era in the treatment of type 1 diabetes, the next step towards better care, as well as improving the effectiveness and safety of therapy. The aim is to present the case of a T1D patient with a borderline total daily dose of insulin being treated with the Medtronic AHCL system in automatic mode. (2) Materials and Methods: A 9-year-old boy, from October 2020, with type 1 diabetes in remission was connected to the Minimed™ 780G (AHCL) system in accordance with the manufacturer's recommendations (daily insulin dose > 8 units, age > 7). Records of the patient's history were collected from visits to The Department of Children's Diabetology, as well as from the Medtronic CareLink™ software and the DPV SWEET program from October 2020 to April 2021. (3) Results: The patient's total daily insulin requirement decreased in the first 6 weeks after the AHCL was connected, which may reflect the remission phase (tight glycemic control with a healthy lifestyle). The lowest daily insulin requirement of 5.7 units was also recorded. In a three-month follow-up of the patient treated with AHCL, it was found that for almost 38% of the days the insulin dose was less than 8 IU. (4) Conclusions: The AHCL system allows safe and effective insulin therapy in automatic mode, as well as in patients with a lower daily insulin requirement. The AHCL system should be considered a good therapeutic option for patients from the onset of T1D, as well in the remission phase.

Indexed as

Diabetes Mellitus, Type 1Blood GlucoseBlood Glucose Self-MonitoringChildHumansHypoglycemic AgentsInsulinInsulin Infusion SystemsMaleBlood GlucoseHypoglycemic AgentsInsulinadvanced hybrid closed loop systemsborderline total daily dose of insulinremissiontype 1 diabetes mellitus

Identifiers

PMID34770502
PMCPMC8587306

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.