Evidence map›Paper›PMID 34770739›Full record

ArticleMolecules (Basel, Switzerland)2021

Validation of the Antioxidant and Enzyme Inhibitory Potential of Selected Triterpenes Using In Vitro and In Silico Studies, and the Evaluation of Their ADMET Properties.

Nilufar Z Mamadalieva, Fadia S Youssef, Hidayat Hussain, Gokhan Zengin, Adriano Mollica, Nawal M Al Musayeib, Mohamed L Ashour, Bernhard Westermann, Ludger A Wessjohann

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Investigating the Anti-Inflammatory Activity ofFoods (Basel, Switzerland) · 2026
    Article
  2. Food science & nutrition · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Chemometric discrimination of eightCurrent research in food science · 2024
    Article
  7. Characterization ofACS omega · 2023
    Article
  8. Triterpenoids fromACS omega · 2023
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Silviridoside: A New Triterpene Glycoside fromMolecules (Basel, Switzerland) · 2022
    Article
  14. Article
  15. Review
  16. Article
  17. The Role ofMolecules (Basel, Switzerland) · 2022
    Article
  18. Article
  19. Article
  20. Metabolomics-Based Profiling ofAntioxidants (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Nilufar Z MamadalievaInstitute of the Chemistry of Plant Substances, Academy Sciences of Uzbekistan, Tashkent 100170, Uzbekistan.ORCID 0000-0003-1756-3638
Fadia S YoussefDepartment of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt.ORCID 0000-0002-5871-2639
Hidayat HussainDepartment of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120 Halle (Saale), Germany.ORCID 0000-0002-8654-8127
Gokhan ZenginDepartment of Biology, Science Faculty, Selcuk University, Konya 42130, Turkey.ORCID 0000-0001-6548-7823
Adriano MollicaDepartment of Pharmacy, University "G. d'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy.ORCID 0000-0002-7242-4860
Nawal M Al MusayeibDepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh 11495, Saudi Arabia.
Mohamed L AshourDepartment of Pharmacognosy, Faculty of Pharmacy, Ain Shams University, Cairo 11566, Egypt.ORCID 0000-0002-9270-6267
Bernhard WestermannDepartment of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120 Halle (Saale), Germany.
Ludger A WessjohannDepartment of Bioorganic Chemistry, Leibniz Institute of Plant Biochemistry, Weinberg 3, 06120 Halle (Saale), Germany.ORCID 0000-0003-2060-8235

Funding

King Saud University Researchers Supporting, King Saud University, Riyadh, Saudi Arabia (RSP-2021/294)
6 · The paper itself

Abstract

The antioxidant and enzyme inhibitory potential of fifteen cycloartane-type triterpenes' potentials were investigated using different assays. In the phosphomolybdenum method, cycloalpioside D (

Indexed as

AntioxidantsChelating AgentsCholinesterase InhibitorsEnzyme InhibitorsFree Radical ScavengersHumansMolecular ConformationMolecular Docking SimulationMolecular Dynamics SimulationMolecular StructureProtease InhibitorsStructure-Activity RelationshipTissue DistributionTriterpenesAntioxidantsChelating AgentsCholinesterase InhibitorsEnzyme InhibitorsFree Radical ScavengersProtease InhibitorsTriterpenesAlzheimer’s diseaseantioxidantsenzyme inhibitioninflammationin vitro assaystriterpenesvirtual screening

Identifiers

PMID34770739
PMCPMC8587851

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.