Evidence map›Paper›PMID 34778697›Full record

ArticleTH open : companion journal to thrombosis and haemostasis2021

Heparin-induced Thrombocytopenia Diagnosis: A Retrospective Study Comparing Heparin-induced Platelet Activation Test to

Marie-Caroline Gonthier, Nicolas Gendron, Philippine Eloy, Marie-Charlotte Bourrienne, Martine Alhenc-Gelas, Claire Pouplard, Bernard Tardy, Jean Szymezak, Charles Burdet, Vasiliki Gkalea and 2 more

Open access · goldAbstract read
In one paragraph

Article in TH open : companion journal to thrombosis and haemostasis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Observational
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  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Marie-Caroline GonthierLaboratory of Vascular Translational Science, Université de Paris, INSERM, et Laboratoire d'Hématologie, AH-HP, Bichat-Claude Bernard Hospital, Paris, France.
Nicolas GendronLaboratory of Vascular Translational Science, Université de Paris, INSERM, et Laboratoire d'Hématologie, AH-HP, Bichat-Claude Bernard Hospital, Paris, France.ORCID 0000-0003-4852-4738
Philippine EloyDépartement d'Epidémiologie, Biostatistique et Recherche Clinique, AH-HP, Bichat-Claude Bernard Hospital, Paris, France.
Marie-Charlotte BourrienneLaboratory of Vascular Translational Science, Université de Paris, INSERM, et Laboratoire d'Hématologie, AH-HP, Bichat-Claude Bernard Hospital, Paris, France.ORCID 0000-0003-0125-9236
Martine Alhenc-GelasHematology Department and Biosurgical Research Lab (Carpentier Foundation), Assistance Publique Hôpitaux de Paris.Centre-Université de Paris (APHP-CUP), Paris, France.
Claire PouplardCHRU Tours, Service d'hématologie-hémostase, Université de Tours, Tours, France.
Bernard TardyInserm CIC 1408 CHU Saint Etienne, Saint-Etienne, France.
Jean SzymezakLaboratoire d'hématologie, CHU Robert Debré, Reims, France.
Charles BurdetDépartement d'Epidémiologie, Biostatistique et Recherche Clinique, AH-HP, Bichat-Claude Bernard Hospital, Paris, France.
Vasiliki GkaleaLaboratory of Vascular Translational Science, Université de Paris, INSERM, et Laboratoire d'Hématologie, AH-HP, Bichat-Claude Bernard Hospital, Paris, France.
Dorothée FailleLaboratory of Vascular Translational Science, Université de Paris, INSERM, et Laboratoire d'Hématologie, AH-HP, Bichat-Claude Bernard Hospital, Paris, France.
Nadine AjzenbergLaboratory of Vascular Translational Science, Université de Paris, INSERM, et Laboratoire d'Hématologie, AH-HP, Bichat-Claude Bernard Hospital, Paris, France.
Université Claude Bernard Lyon 1 · FRHôpital Robert-Debré · FRInserm · FRUniversité de Tours · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laboratory confirmation of heparin-induced thrombocytopenia (HIT) is of crucial importance and remains challenging and relies on platelet functional assays highlighting the presence of heparin-dependent platelet-activating antibodies in patient serum or plasma. Platelet functional assays using washed platelets include the

Indexed as

14 C-serotonin release assayheparin induced platelet activation testheparin-induced thrombocytopenialaboratory diagnosisPF4/heparin antibodies

Identifiers

PMID34778697
PMCPMC8577886
OpenAlexW3203031660

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.