Evidence map›Paper›PMID 34781637›Full record

ArticleKidney research and clinical practice2022

Pericoronary fat attenuation index in computed tomography angiography is associated with mortality in end-stage renal disease.

Nam-Jun Cho, Bo Da Nam, Samel Park, Hyoungnae Kim, Hyunjin Noh, Jin Seok Jeon, Dong Cheol Han, Eun Young Lee, Hyo-Wook Gil, Soon Hyo Kwon

Open access · diamondAbstract read
In one paragraph

Article in Kidney research and clinical practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Nam-Jun ChoDepartment of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Republic of Korea.
Bo Da NamDepartment of Radiology, Soonchunhyang University Seoul Hospital, Seoul, Republic of Korea.
Samel ParkDepartment of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Republic of Korea.
Hyoungnae KimDepartment of Internal Medicine, Soonchunhyang University Seoul Hospital, Seoul, Republic of Korea.
Hyunjin NohDepartment of Internal Medicine, Soonchunhyang University Seoul Hospital, Seoul, Republic of Korea.
Jin Seok JeonDepartment of Internal Medicine, Soonchunhyang University Seoul Hospital, Seoul, Republic of Korea.
Dong Cheol HanDepartment of Internal Medicine, Soonchunhyang University Seoul Hospital, Seoul, Republic of Korea.
Eun Young LeeDepartment of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Republic of Korea.
Hyo-Wook GilDepartment of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Republic of Korea.
Soon Hyo KwonDepartment of Internal Medicine, Soonchunhyang University Seoul Hospital, Seoul, Republic of Korea.
Soonchunhyang University Hospital Seoul · KRSoonchunhyang University · KR

Funding

Korean Ministry of Science and Information and Communications Technology NRF-2019M3E5D3073102Soonchunhyang University
6 · The paper itself

Abstract

backgroundAn increased pericoronary fat attenuation index (FAI) on computed tomography angiography (CTA) is associated with increased all-cause and cardiac mortality in the general population. However, the ability of pericoronary FAI to predict long-term outcomes in chronic kidney disease (CKD) patients is unknown.

methodsIn this single-center retrospective longitudinal cohort study, we assessed the utility of CTA-based pericoronary FAI measurement to predict mortality of CKD patients, including those with end-stage renal disease (ESRD). Mapping and analysis of pericoronary FAI involved three major proximal coronary arteries. The prognostic value of pericoronary FAI for long-term mortality was assessed with multivariable Cox regression models.

resultsAmong 268 CKD participants who underwent coronary CTA, 209 participants with left anterior descending artery (LAD) FAI measurements were included. The pericoronary FAI measured at the LAD was not significantly associated with adjusted risk of allcause mortality (hazard ratio [HR], 2.08; 95% confidence interval [CI], 0.94-3.51) in any CKD group. However, ESRD patients with elevated pericoronary FAI values had a greater adjusted risk of all-cause mortality compared with the low-FAI group (HR, 2.26; 95% CI, 1.11-4.61).

conclusionThe pericoronary FAI measured at the LAD predicted long-term mortality in patients with ESRD, which could provide an opportunity for early primary intervention in ESRD patients.

Indexed as

Chronic kidney diseaseCoronary inflammationEnd-stage renal diseaseMortality

Identifiers

PMID34781637
PMCPMC8816413
OpenAlexW3213959476

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.