Evidence map›Paper›PMID 34785264›Full record

SynthesisJournal of affective disorders2022

The global prevalence of depression and anxiety among doctors during the covid-19 pandemic: Systematic review and meta-analysis.

G Johns, V Samuel, L Freemantle, J Lewis, L Waddington

Open access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Journal of affective disorders, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 9 pooled it
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 9 syntheses or guidelines pooled it, 114 citations in OpenAlex.

  1. Pooled it
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  7. Anxiety Linked to COVID-19: A Systematic Review Comparing Anxiety Rates in Different Populations.International journal of environmental research and public health · 2022
    Pooled it
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  10. Article
  11. Article
  12. Perceived Stress Among Medical Doctors Working in Nepal: An Observational Study.JNMA; journal of the Nepal Medical Association · 2026
    Observational
  13. Article
  14. A Comprehensive Review on Anxiolytic Effect ofFood science & nutrition · 2025
    Review
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  17. Article
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  20. Suicide risk factors among Lithuanian medical doctors and residents.Archives of public health = Archives belges de sante publique · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

G JohnsCardiff University, School of Psychology. Electronic address: g.johns2@nhs.net.
V SamuelCardiff University, School of Psychology.
L FreemantleCornwall Partnership NHS Foundation Trust.
J LewisAneurin Bevan University Health Board, NHS Wales.
L WaddingtonCardiff University, School of Psychology.
Cardiff University · GBAneurin Bevan University Health Board · GBCornwall Partnership NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis review provides an estimate of the global prevalence of depression and anxiety symptoms among doctors, based on analysis of evidence from the first year of the COVID-19 pandemic.

methodsA systematic review was conducted to identify suitable studies. Final searches were conducted on 3rd March 2021. Papers were initially screened by title and abstract, based on pre-agreed inclusion criteria, followed by full-text review of eligible studies. Risk of bias was assessed using the Joanna Briggs Checklist for Prevalence Studies. Data from studies rated as low or medium risk of bias were pooled using a random-effects meta-analysis. Sensitivity and subgroup analyses were conducted to explore heterogeneity.

resultsFifty-five studies were included after full-text review. Of these, thirty studies were assessed as low or medium risk of bias and were included in primary analyses. These comprised twenty-six studies of depression (31,447 participants) and thirty studies of anxiety (33,281 participants). Pooled prevalence of depression and anxiety was 20.5% (95% CI 16.0%-25.3%) and 25.8% (95% CI 20.4%-31.5%) respectively.

interpretationEvidence from the first year of the pandemic suggests that a significant proportion of doctors are experiencing high levels of symptoms of depression and anxiety, although not conclusively more so than pre-pandemic levels. Differences in study methodology and variation in job demands may account for some of the observed heterogeneity. LIMITATIONS: Findings must be interpreted with caution due to the high heterogeneity and moderate risk of bias evident in the majority of included studies.

Indexed as

COVID-19PandemicsAnxietyDepressionHumansPrevalenceSARS-CoV-2anxietyCoronavirusCovid-19depressionDoctorsPhysicians

Identifiers

PMID34785264
PMCPMC8596335
OpenAlexW3211354317

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.