Evidence map›Paper›PMID 34786208›Full record

ArticleMolecular therapy. Nucleic acids2021

Staem5: A novel computational approachfor accurate prediction of m5C site.

Di Chai, Cangzhi Jia, Jia Zheng, Quan Zou, Fuyi Li

Abstract read
In one paragraph

Article in Molecular therapy. Nucleic acids, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. XGBoost framework with feature selection for the prediction of RNA N5-methylcytosine sites.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Article
  7. Predicting Pseudouridine Sites with Porpoise.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  8. Review
  9. Article
  10. Article
  11. Biological roles of RNA mBiomarker research · 2022
    Review
  12. MLACP 2.0: An updated machine learning tool for anticancer peptide prediction.Computational and structural biotechnology journal · 2022
    Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Di ChaiSchool of Science, Dalian Maritime University, Dalian 116026, China.
Cangzhi JiaSchool of Science, Dalian Maritime University, Dalian 116026, China.
Jia ZhengSchool of Science, Dalian Maritime University, Dalian 116026, China.
Quan ZouYangtze Delta Region Institute (Quzhou), Quzhou, China.
Fuyi LiDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, 792 Elizabeth Street, Melbourne, VIC 3000, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

5-Methylcytosine (m5C) is an important post-transcriptional modification that has been extensively found in multiple types of RNAs. Many studies have shown that m5C plays vital roles in many biological functions, such as RNA structure stability and metabolism. Computational approaches act as an efficient way to identify m5C sites from high-throughput RNA sequence data and help interpret the functional mechanism of this important modification. This study proposed a novel species-specific computational approach, Staem5, to accurately predict RNA m5C sites in

Indexed as

ensemble learningm5C sitesmachine learningRNA modificationsequence analysisstacking

Identifiers

PMID34786208
PMCPMC8571400

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.