Evidence map›Paper›PMID 34790377›Full record

ArticleJournal of gastrointestinal oncology2021

Long non-coding RNA

Ling Gai, Yeqing Huang, Lingling Zhao, Feng Li, Zhixiang Zhuang

Abstract read
In one paragraph

Article in Journal of gastrointestinal oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ling Gai *Department of Oncology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
Yeqing Huang *Department of Chemotherapy, Affiliated Hospital of Nantong University, Nantong, China.
Lingling ZhaoDepartment of Medical Ultrasound, The First People's Hospital of Nantong, Nantong, China.
Feng LiDepartment of Laboratory Medicine, Affiliated Hospital of Nantong University, Nantong, China.
Zhixiang ZhuangDepartment of Oncology, The Second Affiliated Hospital of Soochow University, Suzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEsophageal cancer (EC) is a common malignant tumor of the digestive tract, the treatment of which involves surgery combined with radiotherapy and chemotherapy, as well as other comprehensive types of treatment. The pathogenesis of EC remains unclear, which hinders the development of clinical therapy and the identification of molecular targets for this disease. Long non-coding RNAs (lncRNAs) have been shown to be associated with the malignant biological behavior of EC, but the specific molecular mechanisms underlying the carcinogenesis of EC are not fully understood.

methodsReverse transcription-quantitative PCR (RT-qPCR) was applied to measure the lncRNA HAGLR opposite strand lncRNA (

results

conclusions

Indexed as

esophageal carcinomaHAGLR opposite strand lncRNA (HAGLROS)Long non-coding RNA (lncRNA)microRNA-206 (miR-206)notch receptor 3 (NOTCH3)

Identifiers

PMID34790377
PMCPMC8576203

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.