Evidence map›Paper›PMID 34790380›Full record

ArticleJournal of gastrointestinal oncology2021

Comprehensive bioinformatics analyses identified Homeobox B9 as a potential prognostic biomarker and therapeutic target for gastric cancer.

Xiaofei Li, Shujia Chen, Yinghui Zhu, Jiayue Fei, Liaoyuan Song, Guoyan Sun, Wei Niu, Lianyi Guo, Jiwei Wang

Open access · diamondAbstract read
In one paragraph

Article in Journal of gastrointestinal oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.1field-weighted citation impact, top 61% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xiaofei Li *Department of Gastroenterology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Shujia Chen *Department of Gastroenterology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Yinghui ZhuDepartment of Gastroenterology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Jiayue FeiDepartment of Gastroenterology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Liaoyuan SongDepartment of Gastroenterology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Guoyan SunDepartment of Gastroenterology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Wei NiuDepartment of Gastroenterology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Lianyi GuoDepartment of Gastroenterology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, China.
Jiwei WangDepartment of Gastrointestinal Surgery, Xuzhou Central Hospital, Xuzhou, China.
Jinzhou Medical University · CNXuzhou Central Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Homeobox B (

methodsThe Oncomine, Gene Expression Profiling Interactive Analysis (GEPIA), cBioPortal, UALCAN, Kaplan-Meier plotter, and the GeneMANIA databases were used to analyze the messenger RNA (mRNA) expression levels, prognostic value, and gene-gene interaction network of the

resultsThe expression of

conclusionsHOXB family members have different degrees of abnormal expression in GC. High

Indexed as

Gastric cancer (GC)Homeobox B9 (HOXB9)Homeobox B family (HOXB family)prognosis biomarkertherapeutic target

Identifiers

PMID34790380
PMCPMC8576221
OpenAlexW3208923340

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.