ArticleNature communications2021
Generation of a Gluconobacter oxydans knockout collection for improved extraction of rare earth elements.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed.
- Bioleaching of olivine and enstatite with formation of Mg-oxalate mediated by engineered Gluconobacter oxydans.Scientific reports · 2026Article
- Discordance Between 16S rRNA Similarity and Genome-Based Species Boundaries in Gluconobacter.MicrobiologyOpen · 2026Article
- Urban Biomining of Rare Earth Elements: Current Status and Future Opportunities.ACS environmental Au · 2026Review
- Draft genome sequences of four phosphate-solubilizing microbes of the familyMicrobiology resource announcements · 2025Article
- Cross-species comparison of ultramafic rock bio-accelerated weathering performance.Scientific reports · 2025Article
- High efficiency rare earth element bioleaching with systems biology guided engineering of Gluconobacter oxydans.Communications biology · 2025Article
- Article
- Direct genome-scale screening of Gluconobacter oxydans B58 for rare earth element bioleaching.Communications biology · 2025Article
- Bio-accelerated weathering of ultramafic minerals with Gluconobacter oxydans.Scientific reports · 2025Article
- Emerging role of rare earth elements in biomolecular functions.The ISME journal · 2025Review
- Living plastics from plasticizer-assisted thermal molding of silk protein.Nature communications · 2025Article
- Synthetic microbiology in sustainability applications.Nature reviews. Microbiology · 2024Review
- Scalable and Consolidated Microbial Platform for Rare Earth Element Leaching and Recovery from Waste Sources.Environmental science & technology · 2024Article
- Cytoprotective Metal-Phenolic Network Sporulation to Modulate Microalgal Mobility and Division.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Genomic characterization of rare earth binding by Shewanella oneidensis.Scientific reports · 2023Article
- Green Extractants in Assisting Recovery of REEs: A Case Study.Molecules (Basel, Switzerland) · 2023Article
- Article
- Harnessing synthetic biology for sustainable biomining with Fe/S-oxidizing microbes.Frontiers in bioengineering and biotechnology · 2022Review
- Efficient Production of 2,5-Diketo-D-gluconic Acid by Reducing Browning Levels DuringFrontiers in bioengineering and biotechnology · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Bioleaching of rare earth elements (REEs), using microorganisms such as Gluconobacter oxydans, offers a sustainable alternative to environmentally harmful thermochemical extraction, but is currently not very efficient. Here, we generate a whole-genome knockout collection of single-gene transposon disruption mutants for G. oxydans B58, to identify genes affecting the efficacy of REE bioleaching. We find 304 genes whose disruption alters the production of acidic biolixiviant. Disruption of genes underlying synthesis of the cofactor pyrroloquinoline quinone (PQQ) and the PQQ-dependent membrane-bound glucose dehydrogenase nearly eliminates bioleaching. Disruption of phosphate-specific transport system genes enhances bioleaching by up to 18%. Our results provide a comprehensive roadmap for engineering the genome of G. oxydans to further increase its bioleaching efficiency.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.