ReviewBest practice & research. Clinical rheumatology2021
Role of diet in hyperuricemia and gout.
Review in Best practice & research. Clinical rheumatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 102 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
102 citing papers in PubMed, 3 syntheses or guidelines pooled it, 224 citations in OpenAlex.
- Nighttime sleep duration and the prevalence of hyperuricemia: a systematic review and network meta-analysis.Frontiers in neuroscience · 2025Pooled it
- Effect of tea intake on genetic predisposition to gout and uric acid: a Mendelian randomization study.Frontiers in endocrinology · 2023Pooled it
- Efficacy and safety of Danggui Niantong Decoction in patients with gout: a systematic review and meta-analysis.Frontiers in pharmacology · 2023Pooled it
- Effective xanthine oxidase inhibitor urate lowering therapy in gout is linked to an emergent serum protein interactome of complement and inflammation modulators.Scientific reports · 2024Trial
- Efficacy and safety of orlistat in male patients with overweight/obesity and hyperuricemia: results of a randomized, double-blind, placebo-controlled trial.Lipids in health and disease · 2024Trial
- Article
- Clinical and inflammatory factors associated with prevalent gout in a Brazilian hospital population.Clinics (Sao Paulo, Brazil) · 2026Article
- Uric Acid and Chronic Kidney Disease.Kidney medicine · 2026Review
- Dietary intake and hyperuricemia among US adults: A matched case-control analysis of NHANES 2001-2020.Medicine · 2026Article
- Formulation-dependent kinetics ofMicrobiology spectrum · 2026Article
- Negative and nonlinear association between oxidative balance score and hyperuricemia: a cross-sectional analysis based on the NHANES database.Clinical rheumatology · 2026Article
- Effects of Processing on Antinutrients, Bioactives and Functional Properties of Bamboo Shoots (Foods (Basel, Switzerland) · 2026Article
- Age modifies the relationship between ultra-processed food intake and hyperuricemia: findings from NHANES 1999-2018.BMC public health · 2026Article
- Correlation of skeletal muscle mass and visceral fat area with hyperuricemia in male adolescents.BMC endocrine disorders · 2026Article
- Uncommon Presentation of Giant Tophaceous Gout in the Hand: A Case Report.Current rheumatology reviews · 2026Article
- The gut-joint axis in gout: microbial outer membrane vesicles and mFrontiers in immunology · 2026Review
- Assessment of health-related quality of life of patients with gout and hyperuricemia in the Tianjin area according to the SF-6Dv2 scale.Frontiers in public health · 2026Article
- Pathological characteristics of traditional Chinese medicine Shi Zheng and related therapeutic formula, effective compounds: a general review.Chinese medicine · 2025Review
- Higher cardiometabolic index elevates the risk of hyperuricemia in the elderly: findings from the China health and retirement longitudinal study.Annals of medicine · 2025Article
- Association of added sugar intake and its forms with hyperuricemia in general adults: the TCLSIH cohort study.European journal of nutrition · 2025Article
42 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundGout is the most common form of inflammatory arthritis, affecting 41 million adults worldwide. The global burden of gout has been increasing over the last three decades, yet its management remains suboptimal. The primary aim of this manuscript is to review the impact of various diets such as the DASH, Mediterranean, and low purine diets; weight loss; and individual foods, including alcohol, caffeine, cherry, dairy, high-fructose corn syrup, omega-3 fatty acids, and vitamin C on hyperuricemia and clinical gout outcomes such as flares and tophi.
conclusionFew studies to date have specifically evaluated the effect of various dietary approaches on hyperuricemia among people with gout and on gout-specific outcomes. Overall, the dietary factors appear to have a small effect on serum urate levels, and their impact on the long-term clinical course of gout is uncertain. Limited evidence suggests that avoidance of certain foods and beverages may decrease the frequency of gout flares. Weight loss may be beneficial for prevention as well as treatment of gout. Urate-lowering therapy remains the mainstay of therapy, with diet and dietary factors studied to date playing a limited role in the definitive management of gout.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.