ArticleJournal of atherosclerosis and thrombosis2022
Weight Change Since Age 20 and the Risk of Cardiovascular Disease Mortality: A Prospective Cohort Study.
Article in Journal of atherosclerosis and thrombosis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Alcohol consumption and the risk of heart failure: the Suita Study and meta-analysis of prospective cohort studies.Environmental health and preventive medicine · 2023Pooled it
- Bodyweight increase since early adulthood as a risk factor for mobility decline: a 7-year longitudinal study of 10,316 Japanese adults aged ≥ 40 years.Archives of public health = Archives belges de sante publique · 2026Article
- Weight change and the risk of cardiovascular disease in patients with hypertension: A primary-care cohort study.Journal of global health · 2024Article
- Relationships of Weight Change from 20 Years of Age with the Risks of All-Cause and Cardiovascular Mortality in Patients with Chronic Kidney Disease.Journal of atherosclerosis and thrombosis · 2024Observational
- Association between underweight and risk of heart failure in diabetes patients.Journal of cachexia, sarcopenia and muscle · 2024Article
- Blood pressure per the 2017 ACC/AHA and 2018 ESC/ESH guidelines and heart failure risk: the Suita Study.Hypertension research : official journal of the Japanese Society of Hypertension · 2023Article
- Life satisfaction and the risk of atherosclerotic cardiovascular disease in the general Japanese population: the Suita Study.Environmental health and preventive medicine · 2023Article
- QRS transitional zone rotations and the risk of atrial fibrillation: the Suita Study.Heart and vessels · 2022Article
- Association Between Weight Change and Increased Likelihood of Abdominal Aortic Calcification Among Men.Journal of the Endocrine Society · 2022Article
- The Lifelong Health Support 10: a Japanese prescription for a long and healthy life.Environmental health and preventive medicine · 2022Review
- Impact of weight change since a young age on cardiovascular mortality risk: a pooled analysis of Japanese epidemiological evidence.Environmental health and preventive medicine · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimWeight change could have many health outcomes. This study aimed to investigate the association between weight change and mortality risk due to total cardiovascular disease (CVD), ischemic heart disease (IHD), and stroke among Japanese.
methodsWe used Suita Study data from 4,746 people aged 30-79 years in this prospective cohort study. Weight change was defined as the difference between baseline weight and weight at age 20. We used Cox proportional hazards models to calculate hazard ratios (HRs) and 95% confidence intervals (CIs) of total CVD, IHD, and stroke mortality for 1) participants with a weight change (＞10, 5 to 10, -5 to -10, and ＜-10 kg) compared to those with stable weight (-4.9 to 4.9 kg) and 2) participants who moved from one body mass index category (underweight, normal weight, or overweight) to another compared to those with normal weight at age 20 and baseline.
resultsWithin a median follow-up period of 19.9 years, the numbers of total CVD, IHD, and stroke mortality were 268, 132, and 79, respectively. Weight loss of ＞10 kg was associated with the increased risk of total CVD mortality 2.07 (1.29, 3.32) and stroke mortality 3.02 (1.40, 6.52). Moving from normal weight at age 20 to underweight at baseline was associated with the increased risk of total CVD, IHD, and stroke mortality: 1.76 (1.12, 2.77), 2.10 (1.13, 3.92), and 2.25 (1.05, 4.83), respectively.
conclusionWeight loss, especially when moving from normal to underweight, was associated with the increased risk of CVD mortality.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.