Evidence mapPaperPMID 34804369Full record

ReviewOxidative medicine and cellular longevity2021

Theaflavin Chemistry and Its Health Benefits.

Zhiguo Shan, Muhammad Farrukh Nisar, Mingxi Li, Chunhua Zhang, Chunpeng Craig Wan

RetractedOpen access · hybridAbstract readReviewRetracted Publication
In one paragraph

Review in Oxidative medicine and cellular longevity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 71 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Retracted: Theaflavin Chemistry and Its Health Benefits.Oxidative medicine and cellular longevity · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Phytochemicals and Vitamin D for a Healthy Life and Prevention of Diseases.International journal of molecular sciences · 2023
    Review
  14. Antibacterial Effects of Theaflavins againstFoods (Basel, Switzerland) · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Green Tea Catechins: Nature's Way of Preventing and Treating Cancer.International journal of molecular sciences · 2022
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Zhiguo ShanCollege of Agriculture and Forestry, Pu'er University, Pu'er 665099, China.ORCID https://orcid.org/0000-0002-6165-8258
Muhammad Farrukh NisarJiangxi Key Laboratory for Postharvest Technology and Nondestructive Testing of Fruits & Vegetables, College of Agronomy, Jiangxi Agricultural University, Nanchang 330045, China.ORCID https://orcid.org/0000-0001-8873-1227
Mingxi LiResearch Center of Tea and Tea Culture, College of Agronomy, Jiangxi Agricultural University, Nanchang, Jiangxi, China.ORCID https://orcid.org/0000-0003-3987-017X
Chunhua ZhangCollege of Agriculture and Forestry, Pu'er University, Pu'er 665099, China.ORCID https://orcid.org/0000-0001-9567-0987
Chunpeng Craig WanJiangxi Key Laboratory for Postharvest Technology and Nondestructive Testing of Fruits & Vegetables, College of Agronomy, Jiangxi Agricultural University, Nanchang 330045, China.ORCID https://orcid.org/0000-0001-6892-016X
Jiangxi Agricultural University · CNPuer University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Huge epidemiological and clinical studies have confirmed that black tea is a rich source of health-promoting ingredients, such as catechins and theaflavins (TFs). Furthermore, TF derivatives mainly include theaflavin (TF1), theaflavin-3-gallate (TF2A), theaflavin-3'-gallate (TF2B), and theaflavin-3,3'-digallate (TF3). All of these TFs exhibit extensive usages in pharmaceutics, foods, and traditional medication systems. Various indepth studies reported that how TFs modulates health effects in cellular and molecular mechanisms. The available literature regarding the pharmacological activities of TFs has revealed that TF3 has remarkable anti-inflammatory, antioxidant, anticancer, antiobesity, antiosteoporotic, and antimicrobial properties, thus posing significant effects on human health. The current manuscript summarizes both the chemistry and various pharmacological effects of TFs on human health, lifestyle or aging associated diseases, and populations of gut microbiota. Furthermore, the biological potential of TFs has also been focused to provide a deeper understanding of its mechanism of action.

Indexed as

AgingGastrointestinal MicrobiomeAnimalsAntioxidantsBiflavonoidsCatechinHumansInflammationNeurodegenerative DiseasesOsteoporosisAntioxidantsBiflavonoidsCatechintheaflavin

Identifiers

PMID34804369
PMCPMC8601833
OpenAlexW3212367829

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.