ArticleInternational journal of hypertension2021
Irisin Is Correlated with Blood Pressure in Obstructive Sleep Apnea Patients.
Article in International journal of hypertension, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 18 citations in OpenAlex.
- Research advances in the association between Irisin and obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2025Review
- The role of irisin in predicting obstructive sleep apnea severity among obese individuals: a comparative analysis.Sleep & breathing = Schlaf & Atmung · 2024Article
- Irisin, in women and men: blood pressure, heart rate, obesity and insulin resistance.Frontiers in endocrinology · 2023Article
- Association between irisin and metabolic parameters in nondiabetic, nonobese adults: a meta-analysis.Diabetology & metabolic syndrome · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDespite approximately 95% primary cases of hypertension, secondary hypertension seems to be common with resistant forms. Notably, obstructive sleep apnea (OSA) is known as a common cause of secondary hypertension and has a major characteristic of obesity. Irisin acts as a link between muscles and adipose tissues in obesity, playing an essential role in human blood pressure (BP) regulation. However, whether irisin is associated with secondary hypertension caused by OSA and how it takes effect essentially have not been elucidated. PURPOSE: To investigate the changes of irisin and its relationship with BP in OSA.
methods72 snoring patients finished Epworth Sleep Scale (ESS) evaluation before polysomnography (PSG). BP was the average of three brachial BP values by mercury sphygmomanometer. Serum irisin level was determined by enzyme-linked immunosorbent assay (ELISA). Results were analyzed by SPSS software.
resultsIrisin was higher in the severe and quite severe group than that in control and nonsevere groups (
conclusionsIrisin may serve as a potential biomarker for severity of OSA independently of obesity and imply the development of hypertension.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.